Publications by Orlando S F Alcantara

Publications by authors named "Orlando S F Alcantara"

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Differentiation of functional dendritic cells and macrophages from human peripheral blood monocyte precursors is dependent on expression of p21 (WAF1/CIP1) and requires iron.

Joan L Kramer Ioannis Baltathakis Orlando S F Alcantara David H Boldt

Br J Haematol

June 2002

Iron is required for monocyte/macrophage differentiation of HL-60 leukaemia cells. Differentiation requires induction of the cyclin-dependent kinase inhibitor p21 (WAF1/CIP1), and cell cycle arrest at the G1/S checkpoint. With iron depletion, p21 induction and differentiation are blocked.

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