Publications by authors named "Orlando Abreu Gomes"
A reduction of viral mRNA, proteins and induction of altered morphogenesis reveals the anti-HTLV-1 activity of the labdane-diterpene myriadenolide in vitro.
Camila Pacheco Silveira Martins Orlando Abreu Gomes Marina Lobato Martins Luciana Debortoli de Carvalho Jaqueline Gontijo de Souza
BMC Microbiol
December 2014
Background: Human T-lymphotropic virus 1 (HTLV-1) has been associated with leukemia/lymphoma (ATL) and myelopathy/tropical spastic paraparesis (HAM/TSP), in addition to other inflammatory diseases as well as infection complications. Therapeutic approaches for HTLV-1-related pathologies are limited. The labdane diterpene myriadenolide (AMY) is a natural product that exhibit biological activities, such as anti-inflammatory and antiviral activity as reported for HIV and herpesvirus.
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