Publications by authors named "Orit Raphaeli"

Article Synopsis
  • The study aimed to determine the impact of varying energy and protein levels on the survival of critically ill patients in the ICU, involving 646 adults over a 7-year period.
  • Patients were divided into two groups based on protein intake: low protein (LP) receiving ≤1 g/kg/day and high protein (HP) receiving >1 g/kg/day.
  • Results indicated that younger patients, particularly those without severe conditions like renal failure or sepsis, had better survival rates with appropriate protein intake, emphasizing the need for personalized nutritional approaches in critical care.
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Hypophosphatemia (serum phosphate < 2.5 mg/dL) is a major concern when initiating nutritional support. We evaluated which factors contribute to hypophosphatemia development in critically ill patients, as well as the association between hypophosphatemia and mortality.

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Purpose Of Review: Artificial intelligence has reached the clinical nutrition field. To perform personalized medicine, numerous tools can be used. In this review, we describe how the physician can utilize the growing healthcare databases to develop deep learning and machine learning algorithms, thus helping to improve screening, assessment, prediction of clinical events and outcomes related to clinical nutrition.

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Purpose Of Review: Enteral feeding is the main route of administration of medical nutritional therapy in the critically ill. However, its failure is associated with increased complications. Machine learning and artificial intelligence have been used in intensive care to predict complications.

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Article Synopsis
  • The study examines the relationship between gastrointestinal intolerance during early enteral nutrition (EN) and negative clinical outcomes in critically ill patients.
  • A retrospective analysis of 1584 ICU patients revealed that specific markers, particularly gastric residual volume above 250 mL, are significant predictors of early EN failure and mortality rates within 90 days.
  • The use of machine learning algorithms showed promising prediction performance but suggests the need for additional studies to validate these findings.
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Introduction: Hypophosphatemia may prolong ventilation and induce weaning failure. Some studies have associated hypophosphatemia with increased mortality. Starting or restarting nutrition in a critically ill patient may be associated with refeeding syndrome and hypophosphatemia.

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Early identification of patients at risk of malnutrition or who are malnourished is crucial in order to start a timely and adequate nutritional therapy. Yet, despite the presence of many nutrition screening tools for use in the hospital setting, there is no consensus regarding the best tool as well as inadequate adherence to screening practices which impairs the achievement of effective nutritional therapy. In recent years, artificial intelligence and machine learning methods have been widely used, across multiple medical domains, to aid clinical decision making and to improve quality and efficiency of care.

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Background And Objectives: Cardiovascular diseases, such as coronary heart disease (CHD), are the main cause of mortality and morbidity worldwide. Although CHD cannot be entirely predicted by classic risk factors, it is preventable. Therefore, predicting CHD risk is crucial to clinical cardiology research, and the development of innovative methods for predicting CHD risk is of great practical interest.

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