Publications by authors named "Oriol De Diego"

Aim: To determine long-term survival of patients after cardiac arrest undergoing emergent coronary angiography and therapeutic hypothermia.

Methods: We analysed data from patients treated within the regional STEMI Network from January 2015 to December 2020. The primary endpoint was all-cause mortality at median follow-up.

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Article Synopsis
  • The study examines the impact of different types of first medical contact (FMC), such as EMS, community hospital, PCI hospital, and primary care center, on mortality rates in STEMI patients undergoing primary coronary intervention between 2010-2020.
  • Out of 18,332 patients, those who received care at PCI hospitals and community hospitals showed higher 1-year mortality rates, while patients at primary care centers had better outcomes despite longer delays in treatment.
  • The findings suggest that receiving first medical assistance from PCI and community hospitals may lead to worse survival rates compared to emergency medical services, while primary care centers presented a lower risk and better results overall.
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Article Synopsis
  • - The study aimed to investigate the prevalence and mortality trends of mechanical complications in STEMI (ST-elevation myocardial infarction) over two decades, specifically comparing a pre-pPCI (primary percutaneous coronary intervention) period to a post-pPCI period.
  • - Among 6,033 STEMI patients analyzed, mechanical complications occurred in 135 patients, with free wall rupture (FWR) showing a significant reduction of 60% in the pPCI era compared to the pre-pPCI era.
  • - Despite the reduction in FWR, overall mortality rates for mechanical complications did not show significant changes between the two periods, indicating improvements in treatment may not have drastically altered outcomes.
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Background Coronary artery disease remains a major cause of death despite better outcomes of ST-segment-elevation myocardial infarction (STEMI). We aimed to analyze data from the Ruti-STEMI registry of in-hospital, 28-day, and 1-year events in patients with STEMI over the past 3 decades in Catalonia, Spain, to assess trends in STEMI prognosis. Methods and Results Between February 1989 and December 2017, a total of 7589 patients with STEMI were admitted consecutively.

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Aims: Cardiogenic shock (CS) is an ominous complication of ST-elevation myocardial infarction (STEMI), despite the recent widespread use of reperfusion and invasive management. The Ruti-STEMI-Shock registry analysed the prevalence of and 30-day and 1-year mortality rates in ST-elevation myocardial infarction (STEMI) complicated by CS (STEMI-CS) over the last three decades.

Methods And Results: From February 1989 to December 2018, 493 STEMI-CS patients were consecutively admitted in a well-defined geographical area of ~850,000 inhabitants.

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Background: Coronary care units were established in the 1960s to reduce acute-phase mortality in acute coronary syndrome. In the 21st century, the original coronary care unit concept has evolved into an intensive cardiovascular care unit. The aim of this study was to analyse trend changes in characteristics and mortality of patients admitted to a coronary care unit over the past three decades.

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Background Growth differentiation factor 15 (GDF-15) in ST-elevation myocardial infarction (STEMI) is prognostic in first-generation radioimmunoassays. We examined GDF-15 temporal dynamics in STEMI and its predictive value using a first fully automated GDF-15 electrochemiluminescence assay. Methods In this prospective study, circulating GDF-15 concentration was measured at admission (0 h), 12 h and 24 h in 1026 consecutive STEMI patients treated between February 2011 and May 2016 with primary percutaneous coronary intervention.

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Objective: The aim of the present study was to evaluate the prognostic value of the Stanniocalcin-2/PAPP-A/IGFBP-4 axis in patients with ST-segment elevation myocardial infarction (STEMI).

Methods: Observational cohort study performed in 1085 consecutive STEMI patients treated with early reperfusion between February 2011 and August 2014. Stanniocalcin-2, PAPP-A, and IGFBP-4 were measured using state-of-the art immunoassays.

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Background: The use of β-blocker therapy in the setting of acute coronary syndrome (ACS) associated with cocaine consumption (ACS-ACC) is discouraged due to the risk of coronary vasoconstriction. We examined the prognostic value of β-blocker therapy in a contemporary ACS cohort.

Methods And Results: Prospective, single-center study conducted between January 2001 and December 2014 that examined cocaine use among young (≤50-year-old) consecutive patients admitted with an ACS.

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