Publications by authors named "Orimolade O"

Introduction/background: There is still little data on clinical profile and atrial fibrillation (AF) characteristics in West Africa. Traditionally the risk factor for chronic AF in the sub-region is chronic rheumatic heart disease. However, with the rapid demographic and epidemiologic transition in the sub-region, the risk factors, clinical profile, and complications of AF appear to be changing.

View Article and Find Full Text PDF

Background: Cardiac disorders are found in about half of cases of Noonan syndrome (NS). The most common congenital heart diseases in this syndrome include pulmonary valvular stenosis obstructive or nonobstructive hypertrophic cardiomyopathy (17%). Biventricular hypertrophic cardiomyopathy (HCM) is very rare in this condition.

View Article and Find Full Text PDF
Article Synopsis
  • Non-traumatic acute chest pain (NTACP) is a common issue in emergency departments and can signal acute coronary syndrome (ACS), but there's limited information on how these patients are managed in hospitals, particularly in sub-Saharan Africa.
  • The study aimed to analyze the care process for NTACP patients at a tertiary hospital in Nigeria, focusing on quality indicators essential for improving outcomes in ACS management.
  • Out of 4,306 patients, 225 had NTACP, with a majority presenting late to the emergency department, and only a small fraction received crucial diagnostic tests, highlighting significant gaps in the care provided.
View Article and Find Full Text PDF

Importance: With the high burden of hypertension in sub-Saharan Africa, there is a need for effective, safe and scalable treatment strategies.

Objective: To compare, among Black African adults, the effectiveness and safety of a novel low-dose triple-pill protocol compared with a standard-care protocol for blood pressure lowering.

Design And Setting: Randomized, parallel-group, open-label, multicenter trial conducted in public hospital-based family medicine clinics in Nigeria.

View Article and Find Full Text PDF

Introduction: There has been an upsurge in the reporting of cases of Left Ventricular Noncompaction (LVNC) cardiomyopathy in medical literature in the last 35 years due to advances in medical imaging.The condition was first described in 1926 and the first reported case by echocardiography was in 1984. The American Heart Association considers LVNC a primary cardiomyopathy of genetic origin, while the European Society of Cardiology and the World Health Organization grouped it as an unclassified cardiomyopathy.

View Article and Find Full Text PDF

Background: Heart failure is now a significant contributor to the burden of non-communicable diseases in developing countries like Nigeria which is experiencing epidemiologic and demographic transition. The epidemiology of heart failure in this country is poorly characterized. The aim of the review is to determine the prevalence of heart failure, the associated risk factors, the aetiology, management, and outcomes of the condition in the country.

View Article and Find Full Text PDF

Background: There has been an increase in the reporting of cases of left ventricular noncompaction (LVNC) cardiomyopathy in medical literature due to advances in medical imaging. Patients with LVNC may be asymptomatic or may present with arrhythmias, heart failure, thromboembolism or sudden death. LVNC is typically diagnosed by echocardiography, although there are higher-resolution cardiac imaging techniques such as cardiac magnetic resonance imaging (MRI) to make the diagnosis.

View Article and Find Full Text PDF

There are very few studies in Africans investigating the association between early life exposure to malnutrition and subsequent hypertension in adulthood. We set out to investigate this potential association within an adult cohort who were born around the time of the Biafran War (1968-1970) and subsequent famine in Nigeria. This was a retrospective analysis of Abia State Non-Communicable Diseases and Cardiovascular Risk Factors (AS-NCD-CRF) Survey, a community-based, cross-sectional study that profiled 386 adults (47.

View Article and Find Full Text PDF

Pericarditis and pericardial effusion are commonly associated with hypothyroidism. It is an uncommon association with hyperthyroidism. We present a case of pericarditis/pericardial effusion in a 28-year-old Nigerian lady with hyperthyroidism.

View Article and Find Full Text PDF

The current pandemic of SARS-COV 2 infection (Covid-19) is challenging health systems and communities worldwide. At the individual level, the main biological system involved in Covid-19 is the respiratory system. Respiratory complications range from mild flu-like illness symptoms to a fatal respiratory distress syndrome or a severe and fulminant pneumonia.

View Article and Find Full Text PDF