Improving the Understanding of the Immunopathogenesis of Lymphopenia as a Correlate of SARS-CoV-2 Infection Risk and Disease Progression in African Patients: Protocol for a Cross-sectional Study.

Background: The COVID-19 pandemic, caused by SARS-CoV-2, continues to impact health systems throughout the world with serious medical challenges being imposed on many African countries like Nigeria. Although emerging studies have identified lymphopenia as a driver of cytokine storm, disease progression, and poor outcomes in infected patients, its immunopathogenesis, as well as environmental and genetic determinants, remain unclear. Understanding the interplay of these determinants in the context of lymphopenia and COVID-19 complications in patients in Africa may help with risk stratification and appropriate deployment of targeted treatment regimens with repurposed drugs to improve prognosis.

Relapse precipitants in Nigerian drug abusers.

Objective: To determine the precipitants of relapse among patients admitted to a Psychiatric Hospital in Nigeria for substance abuse.

Patients And Methods: A cross-sectional survey of consecutive admitted drug abuse patients was carried out at the Psychiatric Hospital, Yaba, Lagos, using Marlatt's categories to measure high risk situations for relapse.

Results: Eighty-two subjects who were mostly male (87.

Specific psychiatric morbidity among diabetics at a Nigerian General Hospital.

Background: In Nigeria, with a rising incidence of diabetes mellitus (DM), there are no controlled studies of specific psychiatric morbidity among sufferers.

Objective: To assess the prevalence of specific psychiatric disorders and general cognitive impairment in patients with diabetes mellitus.

Method: Using Wing's Present State Examination and the Mini-Mental State Examination, we assessed the prevalence of specific psychiatric disorders and cognitive impairment among 100 DM patients attending an out-patient clinic, in comparison with a matched non-clinic sample; and examined the relationship between psychiatric morbidity and clinical variables.

Rehabilitation of heroin and cocaine abusers managed in a Nigerian psychiatric hospital.

Eighty patients, managed primarily for heroin and cocaine dependence at the Drug Rehabilitation Unit of Psychiatric Hospital, Yaba, Lagos, were followed up monthly for a period of 12 months post-discharge and assessed with regard to continued substance use, employment status and illegal activities. The management package included full assessment, detoxification, treatment of associated physical conditions, group therapy sessions, occupational and vocational rehabilitation. The sample was predominantly male (91%), young adults (mean age 29.

Kleine-Levin syndrome: case report.

A case of Kleine-Levin syndrome in a fourteen year old junior high school female student is described. The episodic disorder was characterised by excessive sleep, voracious appetite, irritability, confusion and electro-encephalographic changes. Remission was spontaneous.

Comparative study of psychiatric morbidity among workers at a paint factory in Nigeria.

Inspite of numerous reports on the neurobehavioural effects of paints, there have been no such studies from Nigeria, where there are now many paint factories. The general aim of this study was, to assess the prevalence of specific psychiatric morbidity among workers in a large paint manufacturing factory. Using the Psychiatric Assessment Schedule (PAS), 60 workers (mean age, 38.

Financial cost of treating out-patients with schizophrenia in Nigeria.

Background: An assessment of the monetary costs of treating a group of Nigerian out-patients with schizophrenia, in comparison with insulin-dependent diabetics, was made.

Method: Fifty out-patients with schizophrenia (mean age 42.9) and 40 with diabetes (mean age 41.

Folie-a-deux: report of two incidents.

Two incidents of shared delusions are presented, one between two brothers and the other between an elderly couple. Their presentation and management are discussed. The possible role of projection and overvalued ideas as aetiological factors in Nigerians with shared delusions are highlighted.