Publications by authors named "Oriana D'Anna Mardero"
X-linked retinoschisis (XLRS) is an inherited retinal disorder due to mutations in retinoschisin 1, characterized by impaired central vision secondary to parafoveal cystic cavities and visual field loss by splitting through the retinal nerve fibre layer in the peripheral retina. It is the leading cause of juvenile macular degeneration in males, and currently there is no approved treatment but carbonic anhydrase inhibitors can be used. A retrospective review of the medical records of 17 children with confirmed XLRS seen in the Paediatric Ophthalmology Department of La Paz University Hospital from the 1st of January 2009 to the 1st of June of 2023 was conducted.
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- High myopia is a severe type of myopia with refractive errors over -6.00 SDs or an eye axial length greater than 26 mm, particularly affecting children under 10 years old.
- The article examines genetic factors in early-onset high myopia by analyzing 21 families and suggesting candidate genes based on whole-exome sequencing results.
- Findings indicate that most families had genetic alterations across several proposed genes, highlighting a potential polygenic inheritance pattern, but further research is needed to confirm these genetic impacts on the condition.
To describe a standardized protocol of the dexamethasone intravitreal (DEX) implant Ozurdex (Allergan, Dublin, Ireland) performed in a controlled environment surgical cabin (CESC). Retrospective and observational study conducted on patients who underwent a DEX implant between May 2011 and June 2019, in a third level University Hospital. The controlled environment surgical cabin (ArcSterile, Imex, Valencia, Spain) used in this study was the MB 20 (2 m width, 1.
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