Publications by authors named "Orhan Gazi Yigitbası"

The objective of this study was to evaluate the use of quantum molecular resonance (QMR) energy in phonomicrosurgery. Quantum molecular resonance energy (QMRE) is an innovative technology that provides low temperature cutting and coagulation of tissues and causes minimal tissue damage during the procedure. Because of these features, this technology may offer new possibilities in phonomicrosurgery.

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Objectives: This study aims to compare histopathological results of conventional surgery and transoral radiofrequency ablation in patients with early stage laryngeal carcinoma.

Patients And Methods: Between January 2006 and May 2010, 36 patients (34 males, 2 females; mean age 61.6 years; range 43 to 77 years) who underwent partial laryngectomy in our clinic were retrospectively analyzed.

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Glomus tumors are uncommon benign neoplasms, which rarely occur in the trachea, usually originating from the posterior wall of the distal portion. Most of tracheal glomus tumors are located in the lower two thirds of the trachea. In this article, we present a 50-year-old male patient with a glomus tumor located on the upper third of the posterior wall of the trachea.

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Introduction: Teratoma refers to a neoplasm that recapitulates all three germ layers. Teratomas may be histologically mature and oncologically benign. Teratomas may also be histologically immature while being oncologically benign, or they may harbor malignant components and have the potential to exhibit an aggressive biological behavior.

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Article Synopsis
  • The histopathologic examination of neck dissection specimens from laryngeal cancer patients may reveal thyroid cancer metastases alongside laryngeal cancer.
  • Two out of 74 patients in a study were found to have thyroid papillary carcinoma after undergoing partial laryngectomy and neck dissection, necessitating total thyroidectomy for complete treatment.
  • Despite this rare occurrence, it is crucial to consider the possibility of concurrent thyroid carcinoma in laryngeal cancer patients and the potential need for additional surgery.
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Objectives: In this study we aimed to evaluate the quality of life during, before and after septoplasty in patients who were diagnosed with nasal septal deviation and also to demonstrate the role and importance of acoustic rhinometry and rhinomanometry methods in objectively demonstrating surgical success.

Patients And Methods: This study was carried out in 44 patients undergoing septoplasty surgery. Patients' preoperative complaints were evaluated by Nasal Obstruction Symptom Evaluation (NOSE) scale.

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  • The study aimed to measure vascular endothelial growth factor (VEGF) levels in laryngeal squamous cell carcinoma (LSCC) tissues and assess its correlation with microvessel density (MVD) and other clinical factors.
  • Out of 27 patients initially considered, 25 were included, with the majority having well or moderately differentiated tumors, but the correlation between VEGF levels, MVD, and clinicopathological factors was found to be non-significant.
  • Results indicated that while VEGF is expressed in LSCC, we could not establish any statistical relationships between it, MVD, and the various clinical factors measured.
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  • The study aimed to evaluate the effectiveness of piracetam and acyclovir in treating sudden hearing loss among 81 patients.
  • All participants, averaging 40.4 years old, were categorized into four treatment groups with varying combinations of these medications.
  • Results showed no significant differences in hearing improvements across the treatment groups, indicating that acyclovir and piracetam did not provide additional benefits.
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Patients suffering from bone metastases of follicular thyroid carcinoma (FTC) have a poor prognosis because of the lack of effective treatment strategies. The overexpression of epidermal growth factor receptor (EGFR) associated with increased vascularity has been implicated in the pathogenesis of FTC and subsequent bone metastases. We hypothesized that inhibiting the phosphorylation of the EGFR and vascular endothelial growth factor receptor (VEGFR) by AEE788, a dual tyrosine kinase inhibitor of EGFR and VEGFR, in combination with paclitaxel would inhibit experimental FTC bone lesions and preserve bone structure.

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A primary alveolar soft part sarcoma arising in the nasal-paranasal sinuses region is quite rare. In this report, a 14-year-old boy with typical features of alveolar soft part sarcoma of the nasal and paranasal sinuses is presented. Treatment was surgical excision of the mass combined with radiotherapy.

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A 63-year-old man presented with malignant fibrous histiocytoma of the larynx occurring 16 years after radiation treatment for squamous cell carcinoma of the larynx. Postirradiation sarcoma of the larynx is an unusual tumor. The location, the histopathologic and immunohistochemical appearance of the tumor, and the time elapsed since the initial treatment make it probable that this tumor is associated with prior radiation treatment.

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