Publications by authors named "Orfhlaith E O'Sullivan"

Article Synopsis
  • The study aimed to compare the risks and outcomes of obstetric anal sphincter injury (OASI) between obese and non-obese women after childbirth.
  • Researchers analyzed data from 349 women, finding that while obese women had higher rates of gestational diabetes, there were no significant differences in newborn weight, delivery methods, or overall adverse outcomes post-delivery.
  • Interestingly, non-obese women showed higher rates of anatomical defects related to OASI, suggesting a need for further investigation into these findings.
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Objectives: This study aimed to evaluate the training and self-assessed proficiency of surgeons in the surgical management of pelvic organ prolapse (POP). We focused on the factors that influence decision-making, the surgical techniques employed, the training received, and the management of complications.

Design: A cross-sectional survey.

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Objective: The objective of this study was to assess the impact of the coronavirus pandemic on gynecology surgical training.

Methods: A national cross-sectional online survey was distributed to all trainees and trainers in the higher specialist training program for obstetrics and gynecology in Ireland. The survey consisted of questions on topics which included: the volume of surgical procedures performed before and since the pandemic, confidence in performing various gynecologic procedures before and since the pandemic and questions regarding the impact of the pandemic on wellbeing and work practices.

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Objective: To evaluate the effectiveness of ChatGPT in providing insights into common urinary incontinence concerns within urogynecology. By analyzing the model's responses against established benchmarks of accuracy, completeness, and safety, the study aimed to quantify its usefulness for informing patients and aiding healthcare providers.

Methods: An expert-driven questionnaire was developed, inviting urogynecologists worldwide to assess ChatGPT's answers to 10 carefully selected questions on urinary incontinence (UI).

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Recently, the debate surrounding the use of mesh in urogynecological procedures has intensified, leading to FDA warnings and heightened safety concerns. This clinical opinion emphasizes the vital need to specify mesh types in these procedures, drawing attention to the risk profiles and clinical outcomes associated with various meshes and the procedures that utilize them. A significant issue identified in contemporary literature is the tendency to group diverse mesh types under the same umbrella, disregarding their unique characteristics and applications.

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Introduction And Hypothesis: Post-hysterectomy vault prolapse poses significant challenges to patients and surgeons alike. Despite numerous surgical interventions during initial vaginal hysterectomy to counteract this, a comparative analysis of their efficacy is limited. This study introduces a pioneering technique intended to avert vault prolapse during vaginal hysterectomy by harmoniously merging level 1 and level 2 support.

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Post-embolisation syndrome (PES) is a prevalent complication that occurs in patients following uterine artery embolisation (UAE) for the treatment of uterine fibroids. The aetiology of PES remains incompletely understood, although postulated to result secondary to tissue infarction resulting in release of inflammatory mediators. We followed PRISMA guidelines and performed a systematic review of studies of PES following UAE from inception to October 2022.

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Objectives: To assess the knowledge of the pelvic floor in female university students, including knowledge of pelvic floor structure, function, pelvic floor dysfunction, and pelvic floor muscle exercises (PFMEs).

Methods: The study design is a cross-sectional study via online questionnaire with convenience sampling of female students registered at University College Cork, Ireland for the academic year 2018 to 2019. An online questionnaire was distributed to students at their registered email addresses.

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Introduction: Obesity has been shown to negatively impact pelvic floor support and associated urinary incontinence (UI), however little is known regarding the long-term effect of bariatric surgery on urinary incontinence.

Objective: The aim of this study is to determine the impact of bariatric surgery on female UI at twelve months post-operatively.

Study Design: A prospective cohort study was performed of all patients undergoing bariatric surgery who reported UI between January 2008 to January 2017.

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Introduction And Hypothesis: Postnatal pelvic floor dysfunction (PFD) has a high prevalence and morbidity amongst parturient women. Women should be counselled regarding postnatal PFD. Our aim was to determine urogynaecology providers' knowledge of risk and protective factors for postnatal PFD, and to assess their practice patterns in postnatal PFD counselling.

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Article Synopsis
  • Robotic surgery is becoming crucial for minimally invasive treatment of complex urogynaecological cases, showcasing its effectiveness in challenging procedures.
  • The video demonstrates two specific cases: the removal of a TVT's left arm using both vaginal and robotic methods, and the extraction of problematic paravaginal sutures, one of which had damaged the bladder.
  • The robot-assisted approach provides superior access to pelvic and retropubic areas, enhancing the ability to manage intricate urogynaecological surgeries.
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The use of novel orally administered anticoagulant agents (NOACs) provides new challenges to clinicians in the perioperative care of patients undergoing urogynaecological surgery. We aimed to assess evidence for managing patients taking NOACs before and after urogynaecological surgery. We conducted a literature search in CINAHL, MEDLINE, CENTRAL, Cochrane Library and PubMed for original research articles in the English language on this topic.

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Introduction: Sacrocolpopexy is the gold standard treatment for vault prolapse. Current reported standards regarding surgical approach and technique vary. Our aim was to evaluate the surgical techniques used and identify any consistency.

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It is recognised that urogynaecological symptoms can have a significant impact on patient quality of life (QoL). Many of the QoL questionnaires are long and provide a burden to patients. The aim of this study was to compare patients' responses to utilising equivalent QoL questionnaires in different formats.

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Patient: Female, 57 FINAL DIAGNOSIS: Bladder erosion Symptoms: Haematuria • irritative bladder symptoms • recurrent UTI Medication: - Clinical Procedure: Endoscopic tape resection Specialty: Urology.

Objective: Unusual or unexpected effect of treatment.

Background: Since 1995 over 1 million tension free vaginal slings have been utilized to treat stress incontinence.

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Purpose: To review the safety and effectiveness of robot-assisted hysterectomy compared to traditional open and conventional laparoscopic surgery, differentiating radical, simple total with node staging, and simple total hysterectomy.

Methods: Medline, Embase, the Cochrane library, and the Journal of Robotic Surgery were searched for controlled trials and observational studies with historic or concurrent controls. Data were pooled using random effects meta-analysis.

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Apoptosis and epithelial-mesenchymal transdifferentiation (EMT) occur in stressed tubular epithelial cells and contribute to renal fibrosis. Transforming growth factor (TGF)-beta(1) promotes these responses and we examined whether the processes were interdependent in vitro. Direct (caspase inhibition) and indirect [epidermal growth factor (EGF) receptor stimulation] strategies were used to block apoptosis during TGF-beta(1) stimulation, and the subsequent effect on EMT was assessed.

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Ureteric obstruction is frequently encountered in primary care urology and can lead to damage to the ipsilateral kidney. Relief of all types of obstruction generally leads to the normalization of any deterioration in renal function noted at diagnosis. However, some evidence from animal models suggests that obstruction can cause progressive deleterious effects on renal function and blood pressure control, especially in the presence of preexisting pathologies such as essential hypertension.

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