Denosumab-associated hypocalcemia: Does gender play a role?

Objective: It is well recognized that the presentation, treatment, and outcomes of various diseases may differ between men and women. We recently reported a 7.4% rate of denosumab-associated hypocalcemia in community-dwelling osteoporotic patients.

Bone-Marrow Suppression in Elderly Patients Following Empiric Radioiodine Therapy: Real-Life Data.

Elderly patients with differentiated thyroid cancer (DTC) tend to have more advanced disease at presentation, for which high activities of radioiodine (RAI) are often recommended. However, the 2015 American Thyroid Association guidelines recommend that empirically administered activities of RAI >150 mCi should be avoided in patients >70 years of age, based on calculated bone-marrow exposure according to two dosimetry-based studies. This study aimed to evaluate the effect of RAI treatment on bone-marrow function in elderly DTC patients.

Cushing's syndrome: comparison between Cushing's disease and adrenal Cushing's.

Purpose: The most common etiology of Cushing's syndrome (CS) is an ACTH-producing pituitary adenoma (pitCS), reported as 2-3 times more frequent than primary adrenal CS (adrCS). We aimed to analyze and compare features of patients with pitCS and adrCS.

Methods: A retrospective file review of 196 consecutive patients (age 46.

Predictors of hypoglycemia in hospitalized patients with diabetes mellitus.

Hypoglycemia is common among hospitalized patients with diabetes mellitus (DM), and is associated with increased morbidity and mortality. Identify pre-admission risk factors associated with in-hospital hypoglycemia. Historical prospectively collected data of adult DM patients hospitalized to medical wards between 2011 and 2013.

Long-term outcomes in older patients with hyperglycemia on admission for ischemic stroke.

Aims: Evaluate the association between admission blood glucose (ABG) and mortality in older patients with or without diabetes mellitus (DM) hospitalized for acute ischemic stroke (AIS).

Methods: Observational data of patients ≥65years, admitted for AIS between January 2011 and December 2013. ABG levels were classified to categories: ≤70 (low), 70-110 (normal), 111-140 (mildly elevated), 141-180mg/dl (moderately elevated) and >180mg/dl (markedly elevated).

Sodium levels on admission are associated with mortality risk in hospitalized patients.

Aims: Abnormal sodium values are common among hospitalized patients. We aimed to investigate the association of admission sodium values and mortality.

Methods: Historical prospectively data of adult patients hospitalized to medical wards between January 2011 and December 2013.

Effect of dietary fatty acid composition on fatty acid profiles of polar and neutral lipid tissue fractions in zebra finches, Taeniopygia guttata.

The growing awareness that the fatty acid (FA) composition of the diets of birds, and ultimately their tissues, influence physiological performance variables, such as aerobic capacity, thermosensitivity, digestive efficiency, etc., underscores the need to understand how differences in dietary fatty acid composition actually translate into differences in the fatty acid composition of specific tissues. We quantified the fatty acid profiles of polar and neutral lipid fractions of several tissues in zebra finches (Taeniopygia guttata) and compared these profiles among birds fed either a control diet of only hulled millet, or one of two experimental diets of hulled millet supplemented with either 8% (by mass) sunflower seed oil (omega6-enriched diet) or linseed oil (omega3-enriched diet).