Intravenous lobular capillary haemangioma: ultrasound and histology findings.

Intravenous lobular capillary haemangioma is a rare variant of lobular capillary haemangioma. This article describes the ultrasound and histological findings of such a lesion.

Fine needle biopsy cytology of breast lesions: a review of interpretative difficulties.

Screening mammography and greater community awareness of breast carcinoma have led to an increase in fine needle biopsies of the breast. As a consequence, a wide variety of cytologic patterns have been encountered and studied in benign, proliferative, and malignant breast lesions. We review the main reasons for diagnostic difficulties in breast cytology, the situations in which either a false positive or a false negative diagnosis is possible, as well as conditions whose incorrect typing can lead to inappropriate management.

Granular cell tumour: a pitfall in FNA cytology of breast lesions.

Granular cell tumours of the breast are rare lesions that may mimic an invasive carcinoma. The fine needle aspiration cytology (FNAC) findings in five cases are presented with specific attention to the pitfalls in the cytological diagnosis of these lesions.

Pitfalls in fine needle aspiration cytology.

A review of pitfalls encountered in fine needle aspiration cytology (FNAC) of all organs and tissues and based mainly on the author's 35-year experience of diagnostic FNAC in clinical practice is presented. Diagnostic difficulties are usually related to deviations from common cytological criteria that may occur in some lesions. Others are due to the effects of the sampling procedure or of the preparation of samples.

Fine-needle aspiration cytological findings in five cases of epithelial-myoepithelial carcinoma of salivary glands.

The cytologic features of five cases of epithelial-myoepithelial carcinoma arising in major salivary glands (four parotid and one submandibular gland) are presented. All cases were initially diagnosed as low-grade malignancies. The smears were generally cellular, with no specific architectural pattern.

Lymphadenoma: a report of three cases of an uncommon salivary gland neoplasm.

Aims: Lymphadenoma of the salivary gland is a rare neoplasm that has not been properly characterized. This study describes the clinicopathological features of three cases.

Methods And Results: All three patients were males, ranging in age from 13 to 57 years.

False-positive reports in fine needle biopsy of breast lesions.

A review of the literature reveals considerable variations in the diagnostic accuracy of fine needle biopsy (FNB) of breast lesions between series, partly due to different methods of calculation, different definitions, and insufficient numbers of cases with adequate follow-up to provide reliable statistics. The best larger series have a false-positive rate between 0.2 and 0.

Broadsheet number 57: problems in fine needle biopsy of the thyroid.

The role of fine needle biopsy and cytological diagnosis in the preoperative evaluation of thyroid nodules is reviewed on the basis of the current literature as well as the authors' personal experience. Technical aspects and guidelines for reporting thyroid samples are discussed in some detail. The main emphasis is on diagnostic pitfalls, those which may lead to a false-negative diagnosis, to a false-positive diagnosis or to an erroneous typing of the lesion, and their cytological patterns are described.

Radial scar/complex sclerosing lesion--a problem in the diagnostic work-up of screen-detected breast lesions.

During the first 7.5 years of breast cancer screening in South Australia, 88 radial scar/complex sclerosing lesions were among the mammographically detected abnormalities. A false-positive cytological diagnosis by fine needle biopsy was given in three of 69 such cases with satisfactory smears, a false-positive rate of 4.

[Thyroid cytopathology].

Rigorous techniques of fine-needle sampling, smearing and staining are mandatory for optimizing the value of thyroid cytopathology. As on frozen sections, follicular lesions should be interpreted with caution.

Diagnostic difficulties in the interpretation of fine needle aspirates of salivary gland lesions: the problem revisited.

Cases of salivary gland lesions (n = 325), mainly neoplastic but including a small number of non-neoplastic lesions, investigated by fine needle aspiration (FNA) and with histological correlation, are reviewed. The review identified a number of differential diagnostic problems which are discussed in some detail. One false-positive and eight false-negative diagnoses had been made resulting in a 99.

Rapid method for detecting monoclonality in B cell lymphoma in lymph node aspirates using the polymerase chain reaction.

Aims: To use the polymerase chain reaction to detect monoclonality at the immunoglobulin heavy chain gene locus in cells derived from lymph node aspirates.

Methods: A nested two-stage polymerase chain reaction (PCR) for the VDJ region of the immunoglobulin heavy chain gene was used to detect monoclonality. The total number of cells available for diagnosis by PCR in lymph node aspirates was between 10(4) and 10(5).

Fine needle aspiration in the chest under CT control.

Over a 42 month period 133 patients underwent 148 CT guided biopsies of 104 pulmonary lesions (78%), 21 mediastinal/hilar masses (16%) and 8 pleural lesions (6%). There were 48 cases (32%) complicated by a pneumothorax, of which 13 (9%) required a chest drain. Two cases each of minor haemopneumothorax (1.

Fine needle aspiration in the diagnosis of salivary gland lesions.

Fine needle aspiration biopsy (FNAB) of salivary glands was performed in 187 patients. In 106 patients with satisfactory FNAB smears who proceeded to surgery, the original cytologic diagnosis was compared with subsequent histopathology. There were 74 benign tumours and 25 malignant tumours.

Bilateral testicular and adrenal malignant lymphoma of pre B-cell type.

A rare case of pre B-lymphoblastic lymphoma of the testes and adrenal glands is presented. No lymph node, central nervous system or bone marrow involvement was demonstrated at diagnosis. The primary presentation was of acute unilateral pain and swelling, mimicking simple orchitis.

Immunocytochemical assay for oestrogen receptor in fine needle aspirates of breast cancer by video image analysis.

Assessment of heterogeneity in oestrogen receptor (ER) expression aims to improve prediction of prognosis and treatment assignment in breast cancer. Current assessments are performed manually and are subjective. Automated image analysis as described here objectively quantitates ER in breast cancer nuclei obtained by needle aspiration.

Fine needle aspiration biopsy of salivary gland tumours. Problems and pitfalls.

A review of all fine needle aspiration biopsies of salivary gland lesions performed at the Flinders Medical Centre during a 9-year period revealed a number of cases in which there was a discrepancy between the initial cytology report and the definitive diagnosis by histology examination. The most common problem was that of atypical features in pleomorphic adenoma, raising a suspicion of a low-grade malignant tumour in 4 cases. One mucoepidermoid carcinoma and one acinic cell carcinoma had been wrongly diagnosed as Warthin's tumours on the basis of the presence of sheets of bland epithelial cells with oncocyte-like cytoplasm.

Relationship between ploidy and steroid hormone receptors in primary invasive breast cancer.

The relationship between ploidy, as measured by flow cytometry, and the presence of oestrogen and progesterone receptors was investigated in 145 primary invasive breast cancers. The tumours were considered as an integral group, and as subgroups of lobular and ductal carcinomas. An association was found between the presence of aneuploid stemlines and an absence of oestrogen receptors (ER), for the total tumour population (P less than 0.

Fine needle aspiration cytology in the diagnosis of solid renal and adrenal masses.

In the eight-year period 1977-1984, 83 renal and adrenal mass lesions which were not clearly simple cysts by ultrasonographic examination (US) were investigated by percutaneous fine needle aspiration (FNA) biopsy. Initially, biopsy was often guided by fluoroscopy, later US was by far the most commonly used modality. There were 77 renal and 6 adrenal masses; 69 lesions were malignant and 14 were benign.

Evaluation of cytodiagnosis of cutaneous basal cell carcinoma.

Cytologic and histopathologic diagnoses were assessed independently without clinical details in 150 lesions from 112 consecutive patients. Nine of the lesions (6%) could not be evaluated cytologically because of unsatisfactory smears. Correct cytodiagnosis was obtained in 125 of 141 (89%) evaluable lesions.