Publications by authors named "Orbay Askeroglu"
While single-fraction Gamma Knife radiosurgery (GKRS) has shown efficacy in managing vestibular schwannomas (VSs), some concerns have been raised regarding its safety profile, particularly in the context of hearing preservation. Hypofractionation has emerged as a promising approach to improving the safety profile. This retrospective, single-institution study evaluated patient outcomes following hypofractionated GKRS (hf-GKRS) for treatment-naïve Koos grade IV VSs.
View Article and Find Full Text PDFBackground: Gamma Knife radiosurgery (GKRS) has well-known efficacy in the treatment of idiopathic trigeminal neuralgia (TN). However, few studies have evaluated the effects of GKRS in the treatment of multiple sclerosis (MS)-related TN. This study analyzed the efficacy and complications of GKRS for MS-related TN.
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- MRI is a crucial tool for planning stereotactic radiosurgery (SRS), but it often contains distortions that can affect treatment outcomes.
- This study analyzed 26 MRI datasets for metastatic brain tumors and used software to correct distortions, finding notable discrepancies between uncorrected and corrected tumor volumes.
- The results emphasized the importance of using corrected MRI for SRS plans, as even small distortions can lead to significant treatment inaccuracies.
Objective: Surgery alone for metastatic brain tumors (METs) often results in local recurrence due to microscopic residual tumor tissue. While stereotactic radiosurgery (SRS) is commonly used post-surgery, hypofractionation may be required for large surgical beds. This study evaluated the efficacy and safety of hypofractionated Gamma Knife radiosurgery (hf-GKRS) for the first time as a post-operative adjuvant therapy.
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- Meningiomas in children are rare and have different characteristics compared to adults, with limited existing research on stereotactic radiosurgery (SRS) for this group.
- A study was conducted on 57 pediatric patients treated with single-fraction SRS, evaluating tumor control, complications, and neurological outcomes over a median follow-up of 69 months.
- Results showed high tumor control rates (85.9%) with minimal new neurological deficits (3.5%) and some adverse radiation effects, indicating that SRS is a promising treatment option for difficult-to-treat pediatric meningiomas.
Comparison with control groups of untreated patients suggests that right-breast-cancer patients who receive radiotherapy have a higher rate of heart disease. Dose constraint for heart has been established to minimize radiotherapy-induced cardiotoxicity during left breast cancer treatment. Additionally, it is suggested to minimize the dosage on left anterior descending (LAD) artery.
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