Publications by authors named "Oranit Likhit"
Article Synopsis
- * A study measured the presence of antibodies to mosquito saliva in different macaque species across national parks, revealing high antibody levels, especially against the Culex quinquefasciatus species, indicating significant interaction with mosquito vectors.
- * The research highlights the potential for using mosquito saliva as a biomarker for studying host interactions and pathogen exposure, while also raising concerns about disease transmission between macaques, visitors, and mosquitoes in natural areas.
Article Synopsis
- Japanese encephalitis virus (JEV) is a common cause of encephalitis in Asia, transmitted to humans primarily through mosquito bites, with pigs and birds serving as main hosts.
- This study found JEV neutralizing antibodies in non-human primates (NHPs) and humans in Thailand, indicating natural infection and transmission between species, with seropositivity rates of 14.7% in monkeys and up to 45.2% in humans.
- The results suggest a need for ongoing serological studies at the animal-human interface to monitor JEV, especially given the higher infection rates in older humans.
Chikungunya virus (CHIKV) and Zika virus (ZIKV) are mosquito-borne viruses that have caused several outbreaks worldwide. mosquitoes transmit these viruses mainly through sylvatic and urban transmission cycles. In the sylvatic cycle, nonhuman primates (NHPs) can be infected with CHIKV and ZIKV and may play an essential role as reservoirs for virus transmission.
View Article and Find Full Text PDFFrom 2018 to 2020, the Chikungunya virus (CHIKV) outbreak re-emerged in Thailand with a record of more than 10,000 cases up until the end of 2020. Here, we studied acute CHIKV-infected patients who had presented to the Bangkok Hospital for Tropical Diseases from 2019 to 2020 by assessing the relationship between viral load, clinical features, and serological profile. The results from our study showed that viral load was significantly high in patients with fever, headache, and arthritis.
View Article and Find Full Text PDFObjectives: This study is aimed at determining the role of T cells by assessing the numbers of IFN-- and IL-2-secreting T cells following stimulation with peptides derived from DNA topoisomerase-I protein in Thai SSc patients.
Methods: Fifty Thai SSc patients and 50 healthy controls (HC) joined this study. IFN- and IL-2 levels upon stimulation of T cells with 6 peptides derived from DNA topoisomerase-I protein were determined.