Epidural nalbuphine for post cesarean epidural morphine induced pruritus.

Objective: The aim of the present study was to test the efficacy of epidural nalbuphine 5 mg for prevention of morphine-induced pruritus.

Material And Method: Parturients, ASA I-II scheduled for elective cesarean section under epidural anesthesia were randomized into 3 groups: the placebo group, N-5 group, and N-10 group received 4 ml epidural solution containing morphine 4 mg plus either saline, nalbuphine 5 mg, and nalbuphine 10 mg respectively. Pain score at rest and on movement, incidence and severity of pruritus, sedation score, and pethidine consumption were recorded for 24 hours.