Determination of dose and efficacy of atracurium for rapid sequence induction of anesthesia: A randomised prospective study.

Background And Aims: Succinylcholine and high dose rocuronium are neuromuscular blocking agents commonly used for rapid sequence induction of anesthesia. Their usage is limited or contraindicated in some circumstances. The aim of this study is to determine the dosage and efficacy of atracurium without priming for rapid sequence induction of anesthesia.

Deep neuromuscular blockade for endolaryngeal procedures: A multicenter randomized study.

Objectives/hypothesis: The aim of the present study was to compare the surgical condition between deep neuromuscular blockade (NMB) and moderate NMB.

Study Design: Multicenter, randomized, parallel intervention trial.

Methods: One hundred two patients underwent microscopic endolaryngeal surgery at four university hospitals.

Anesthesia-related complications of caesarean delivery in Thailand: 16,697 cases from the Thai Anaesthesia Incidents Study.

Background: Maternal complications related to anesthesia are low in comparison with the results from obstetric factors in developing countries. The purposes of the present study were to determine the incidence of maternal mortality related to anesthesia, to analyze the causes and to suggest measures to improve anesthetic safety for the parturients.

Material And Method: The present study was part of a multi-center study conducted by the Royal College of Anesthesiologists of Thailand aimed at surveillance of anesthesia-related complications in Thailand.

Factors related to 24-hour perioperative cardiac arrest in geriatric patients in a Thai university hospital.

Background: As a site of the Thai Anesthesia Incidents Study (THAI Study) of anesthetic adverse outcome, the authors continued the institutional data collection to determine the incidence and factors related to 24-hour perioperative cardiac arrest in geriatric patients (aged 65 years and over) representing a Thai university hospital.

Material And Method: Between July 1, 2003 and March 31, 2007, an anesthesia registry was conducted at King Chulalongkorn Memorial Hospital. Anesthesiologists and anesthesia residents were requested to record perioperative variables and adverse outcomes including 24-hour perioperative cardiac arrest on a structural data record form.

The Thai Anesthesia Incident Monitoring Study (Thai AIMS) of endobronchial intubation: an analysis of 1996 incident reports.

Objective: To analyze the clinical course, outcomes, contributing factor, corrective and preventive strategies of accidental endobroncheal intubation (EBI) in the Thai Anesthesia Incident Monitoring Study (Thai AIMS).

Material And Method: This was a prospective descriptive multicenter study of anesthesia-related adverse incidents from 51 hospitals across Thailand from January to June 2007. Possible accidental EBI data were extracted and analyzed using descriptive statistics by 3 reviewers.

The Thai Anesthesia Incidents Study (THAI Study) of ambulatory anesthesia: Part I: Method, geographic distribution and population.

Background: There is a continuing trend to have more elective surgical operations performed on an outpatient basis.

Objective: To determine the proportional distribution of anesthetic procedures performed in ambulatory elective surgery at different levels of hospitals across Thailand.

Material And Method: A prospective and descriptive study was conducted at 20 hospitals comprising seven universities, five regional, four general and four district hospitals across Thailand Consecutive outpatients who were undergoing elective surgical operation were included and their relevant data were selected and extracted for summary by using descriptive statistics.

The Thai anesthesia incidents study (THAI Study) of perioperative death in geriatric patients.

Background: The study was part of the Thai Anesthesia Incidents Study (THAI Study), a multi-centered study conducted by the Royal College of Anesthesiologists of Thailand, aiming to survey anesthetic related complications in Thailand.

Objective: Identify the incidence and factors related to perioperative death in geriatric patients.

Material And Method: During a 12 months period (March 1, 2003 - February 28, 2004), a prospective multicenter descriptive study conducted in 20 hospitals comprising of seven university, five tertiary, four general and four district hospitals across Thailand.

Perioperative myocardial ischemia/infarction: study of incidents from Thai Anesthesia Incidence Study (THAI Study) of 163,403 cases.

Objectives: To analyze incidence, risk factors, clinical course, outcomes of PMI. Degree of anesthesia related to PMI, management, precipitating factors and corrective strategies.

Material And Method: PMI cases were extracted from the Thai Anesthesia Incidents Study (THAI Study) database conducted between February 1, 2003 and January 31, 2004, and analyzed using descriptive statistics.

The Thai Anesthesia Incidents Study (THAI Study) of perioperative death: analysis of risk factors.

Background: National statistical data of mortality and morbidity related to anesthesia have not been reported. The need to comprehensively examine the cause of death as well as other adverse events prompted the first national study in Thailand.

Material And Method: In the Thai Anesthesia Incidents Study (THAI Study), a prospectively defined cohort of patients who underwent anesthesia from February 1, 2003 to January 31, 2004 (n=163,403) was studied.

The Thai Anesthesia Incidents Study (THAI Study) of anesthetic outcomes: II. Anesthetic profiles and adverse events.

Background And Rationale: The purposes of the Thai Anesthesia Incidents Study (THAI Study) of anesthetic outcomes were to survey patients, surgical, anesthetic profiles and determine factors related to adverse events.

Material And Method: A prospective descriptive study of occurrence screening was conducted in 20 hospitals comprised of 7 university, 4 general and 4 district hospitals across Thailand. Anesthesia personnel were required to fill up patient-related, surgical-related, anesthesia-related variables and adverse outcomes on a structured data entry form.

The Thai Anesthesia Incidents Study (THAI Study) of oxygen desaturation.

Objectives: To examine incidents, contributory factors, treatment and outcomes associated with oxygen desaturation during anesthesia practice in Thailand.

Material And Method: Relevant data were extracted from the Thai Anesthesia Incidents Study (THAI Study) database between February 1, 2003 and January 31, 2004 and analyzed by using mainly descriptive statistics.

Results: Four hundred and ninety seven incidents of oxygen desaturation (SpO2 <90 for at least 3min or < or = 85%) were reported.

Intrathecal fentanyl for prevention of shivering in cesarean section.

Objectives: The aim of this randomized double-blind study was to investigate whether 20 microg of intrathecally administered fentanyl would influence the incidence and severity of shivering in patients undergoing cesarean section.

Material And Method: Sixty healthy patients scheduled for cesarean section under spinal anesthesia using 2.2 ml of 0.

Spinal versus epidural anesthesia for cesarean delivery in severe preeclampsia: a prospective randomized, multicenter study.

In this randomized, multicenter study we compared the hemodynamic effects of spinal and epidural anesthesia for cesarean delivery in severely preeclamptic patients. The epidural group (n = 47) received 2% lidocaine with epinephrine 1:400,000, 18-23 mL, followed by 3 mg of morphine after delivery. The spinal group (n = 53) received 2.

Maternal satisfaction to epidural and spinal anesthesia for cesarean section.

Background And Objective: The differences between epidural (EA) and spinal (SA) anesthesia that can affect maternal satisfaction are the procedures, quality of anesthesia and postoperative events. Dominantly, postoperative events such as postdural puncture headache, pruritus and nausea or vomiting after spinal anesthesia are claimed to be its disadvantages. However, maternal satisfactory perception to theses two techniques has not been revealed.

Intermittent apnea and total intravenous anesthesia for microscopic laryngeal surgery.

Intermittent apnea with inhalational anesthesia has been reported to improve the visualization of the larynx but it has some disadvantages from inhalational anesthetics. The authors evaluated the use of total intravenous anesthesia instead of inhalation anesthesia in 30 patients undergoing microscopic laryngeal surgery. Anesthesia was started with propofol, fentanyl and cisatracurium.

Factors related to patient satisfaction regarding spinal anesthesia.

Purpose: Regional anesthesia has been shown to improve the clinically oriented outcome and many studies investigating the use of regional anesthesia have incorporated patient satisfaction measurements. This study was undertaken to find the factors related to patient satisfaction after spinal anesthesia which is the most frequent regional anesthesia conducted.

Method: A prospective descriptive study of spinal anesthesia and post-operative survey of patients on the day after surgery was conducted by collecting pre-operative and intra-operative data on a constructed questionaire.

An optimal dose study of intrathecal morphine in gynecological patients.

Background And Objectives: Post-operative pain after gynecological surgery can be controlled by intrathecal administration of opioids and local anesthetics. Effective intrathecal analgesia can be achieved from low dose narcotics with less adverse effects, prolonged duration and reduced narcotics requirement. Therefore, we undertook a prospective randomized study to find out optimal dose of intrathecal morphine for long lasting post-operative analgesia with less adverse effect in this group of patients.

Efficacy of chamomile-extract spray for prevention of post-operative sore throat.

A randomized, double-blind study was carried out to assess the effect of 111 mg of Chamomile extract spray compared with normal saline spray (placebo) administered before intubation on post-operative sore throat and hoarseness. One hundred and sixty-one ASA (American Society of Anesthesiologists) physical status I, II elective surgical patients were recruited. Forty-two out of 80 patients (52.