Pre-implantation genetic testing for Marfan syndrome using mini-sequencing.

Marfan syndrome (MFS1) is an autosomal dominant condition causing aortopathy including fatal aortic dissection. This study aimed to perform clinical PGT-M in a family with a history of MFS1 for two generations. A family with two members affected by MFS1 approached the hospital for PGT-M.

Early prenatal detection of anterior uterine sacculation resulting from previous cesarean sections.

Anterior uterine sacculation was diagnosed at 15 weeks of gestation in a woman with two previous cesarean sections, based on hourglass appearance of two distinct uterine segments, namely the empty upper segment and the large thinned wall lower segment containing a fetus with posteriorly attached placenta. The pregnancy developed through the bulging weakened anterior wall instead of growing toward the upper segment. Urgent hysterectomy was performed.

Intrauterine Adhesions: Causes and Treatment Outcomes among Thai Women.

Objective: To explore the causes and treatment outcomes of intrauterine adhesions among Thai women.

Material And Method: This retrospective cross-sectional study recorded and analyzed the demographic data, causes, and treatment outcomes of 75 patients who underwent hysteroscopic adhesiolysis between January 2004 and June 2015 at Maharaj Nakhon Chiang Mai Hospital, Chiang Mai, Thailand.

Results: The most common etiology of intrauterine adhesions was a history of early pregnancy termination by curettage (68%).

Recurrence of Endometrioma Following Conservative Ovarian Endometrioma Cystectomy: Laparoscopy versus Laparotomy.

Objective: To investigate the recurrence rate and disease-free interval between laparoscopy versus laparotomy for the conservative surgery of endometrioma.

Material And Method: A retrospective cohort study was conducted. The medical records of reproductive women who underwent conservative ovarian cystectomy surgery (laparoscopy or laparotomy) for endometrioma at Thammasat University Hospital were retrieved.

Antimullerian hormone changes after laparoscopic ovarian cystectomy for endometrioma compared with the nonovarian conditions.

Laparoscopic ovarian cystectomy is recommended for surgical procedure of endometrioma. The negative impact on ovarian reserve following removal had been documented. Little evidence had been reported for nonovarian originated effects.

Impact of hemostasis methods, electrocoagulation versus suture, in laparoscopic endometriotic cystectomy on the ovarian reserve: a randomized controlled trial.

Objective: To evaluate the impact on ovarian reserve between two different methods ofhemostasis after laparoscopic ovarian endometrioma excision.

Material And Method: A randomized controlled study was conducted from January to December 2013 in Thammasat University Hospital, Thailand. Reproductive women, age 18-45years who underwent laparoscopic ovarian cystectomy were randomized in electrocoagulation and suture groups.

Cervical pregnancy with massive bleeding after treatment with methotrexate.

This report describes a catastrophic bleeding following methotrexate treatment of cervical pregnancy and dramatic response to Bakri surgical obstetric silicone (SOS) balloon tamponade in controlling massive bleeding. A 42-year-old woman was diagnosed for cervical pregnancy with a viable fetus at 12 weeks by transvaginal ultrasound. Conservative treatment with intrafetal potassium chloride injection and systemic methotrexate were instituted.

Factors affecting pregnancy rates after microsurgical reversal of tubal sterilization.

The aim of this study was to determine the prognostic factors and pregnancy rates after microsurgical reversal of tubal sterilization. Patients undergoing tubal anastomosis from 2001 to 2008 were included. Relevant data were extracted from their medical records.

Metabolic syndrome and insulin resistance in Thai women with polycystic ovary syndrome.

Objective: To determine the prevalence of metabolic syndrome and insulin resistance in Thai women with polycystic ovary syndrome (PCOS).

Material And Method: Oral glucose tolerance tests were performed in 70 PCOS women. Blood was taken for the measurement of fasting insulin, 2-hr postprandial insulin, lipid profiles, testosterone and sex hormone binding globulin

Results: The prevalence of metabolic syndrome and insulin resistance was 24.

Closed-system solid surface vitrification versus slow programmable freezing of mouse 2-cell embryos.

Purpose: To compare closed-system solid surface vitrification with slow freezing.

Methods: Mouse 2-cell embryos (n = 348) were divided into vitrification, slow freezing and non-frozen groups. For vitrification, embryos were exposed to 10% ethylene glycol (EG), 10% dimethylsulfoxide (DMSO) and 10% fetal bovine serum (FBS) in phosphate-buffered saline (PBS) for 10 min, then transferred into 17.

Gender differences in infertility-related stress and the relationship between stress and social support in Thai infertile couples.

Objective: To study infertility-related stress among men and women and to examine its relationship with the level of perceived social support.

Material And Method: The Fertility Problem Inventory (FPI) and the Personal Resource Questionnaire (PRQ) were translated into Thai and used to assess the level of infertility-related stress and perceived social support, respectively, in 238 infertile subjects.

Results: The global FPI scores for men and women were 154.

Slow programmable and ultra-rapid freezing of human embryos.

Aim: To compare the outcomes of slow freezing with ultra-rapid freezing (URF) of cleavage-stage human embryos on aluminum foil.

Methods: Two-cell mouse embryos were used to test our method of ultra-rapid freezing. The embryos were randomly allocated to a non-frozen control (208 embryos), and slow (204 embryos) or ultra-rapid freezing groups (204 embryos).

Clinical, endocrine and ultrasonographic features of polycystic ovary syndrome in Thai women.

Aim: To study the prevalence, reproductive hormone profiles and ovarian sonographic appearance of Thai women with polycystic ovary syndrome (PCOS).

Methods: One thousand and ninety-five women were screened for oligomenorrhea/amenorrhea, and the clinical symptoms of hyperandrogenism. Ovarian morphology and volume were assessed by ultrasonography in diagnosed cases.