Publications by authors named "Onyire N"
Background: Nigeria has the largest global burden of HIV new infections in children despite global and national concerted efforts at the reduction of mother-to-child transmission of HIV. The goal of this study was to determine the associations between maternal characteristics, practices and mother-to-child transmission of HIV infection among mothers living with HIV.
Methods: This is a hospital-based descriptive cross-sectional study.
Background: The human immunodeficiency virus (HIV) infection and its treatment impact the child's life as well as that of their caregivers. As therapeutic advances are made in the field, improved survival has shifted the focus from morbidity and mortality to quality of life. This study aims to compare the health-related quality of life (HRQoL) of children living with HIV in comparison with an HIV-negative control group and determine its relationship with socio-demographic, clinical, and nutritional variables.
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- A prospective observational study was conducted to examine the pattern and outcomes of Paediatric Lassa fever disease (LFD) in children, due to insufficient documentation in endemic areas.
- Out of 183 children tested for LFD, 24 were positive for the Lassa virus, resulting in a 13.1% positivity rate, with a case fatality rate of 29.2% as seven out of 24 children died during the study.
- Key symptoms associated with higher mortality included convulsions, unconsciousness, bleeding, and poor urine output, highlighting the need for public awareness and early medical intervention for febrile illnesses in children.
Background: Malaria contributes significantly to under-5 morbidity and mortality in Sub-Saharan African countries including Nigeria. The rollback malaria (RBM) initiative and millennium developmental goal 6 are the programs targeted at reduction in malaria burden. The target year here is 2015; it would be needful to determine the impact of these programs on lives of at-risk population.
View Article and Find Full Text PDFCerebral Malaria Complicated by Blindness, Deafness and Extrapyramidal Tract Manifestation.
Ann Med Health Sci Res
August 2015
Cerebral malaria is a severe manifestation of a parasitic infection caused by Plasmodium falciparum. The sequelae of this disease such as blindness, deafness, loss of motor function could be emotionally traumatic and physically disabling. We, therefore, present this case of an 8-year-old boy who presented with high-grade intermittent fever associated with multiple convulsions and prolonged coma.
View Article and Find Full Text PDFBackground: Intestinal helminthiasis is associated with malnutrition in children.
Aim: The objective of this study was to determine the intensity and effect of the common intestinal helminths on the nutritional status of children in Enugu, Nigeria.
Subjects And Methods: A cross-sectional study of 460 children conducted in Enugu metropolis, south-east Nigeria between August and September 2003.
Perinatal Mortality in Southern Nigeria; less than half a decade to the Millennium Developmental Goals.
Ann Med Health Sci Res
July 2011
Background: Perinatal mortality is one of the essential indicators of the health status of a country and by extension its state of development. Reduction in perinatal mortality rate is an important aspect of the MDGs.
Objectives: To determine the perinatal mortality rate (PMR) in 2 tertiary institutions in Southern Nigeria and the factors responsible for the deaths.