Publications by authors named "Onuralp Kurt"
Introduction: Idiopathic hypogonadotrophic hypogonadism with an olfactory deficit is defined as Kallmann syndrome and is distinct from normosmic idiopathic hypogonadotrophic hypogonadism.
Objective: Because olfactory perception not only consists of orthonasally gained impressions but also involves retronasal olfactory function, in this study we decided to comprehensively evaluate both retronasal and orthonasal olfaction in patients with idiopathic hypogonadotrophic hypogonadism.
Methods: This case-control study included 31 controls and 45 idiopathic hypogonadotrophic hypogonadism patients.
Introduction: Boric acid, which has antiseptic and acidic properties, is used to treat external and middle ear infections. However, we have not found any literature about the effect of boric acid powder on middle ear mucosa and inner ear.
Objective: The purpose of this study is to investigate possible ototoxic effects of boric acid powder on cochlear outer hair cell function and histological changes in middle ear mucosa in a rat animal model.
The aim of this study was to evaluate any possible relationship between diabetic state and olfactory and gustatory functions in patients with non-complicated diabetes mellitus type 1 (T1D), and also to present evidence of the association between olfactory and gustatory scores and HbA1c values and disease durations. The study included 39 patients with non-complicated T1D and 31 healthy controls. Clinical characteristics such as age, gender, duration of disease, education levels and biochemical analyses (fasting blood glucose, urea, creatinine, total cholesterol, low-density lipoprotein-cholesterol (LDL-C), high-density lipoprotein (HDL-C), triglyceride, HbA1c, C-peptide, postprandial blood glucose) were measured.
View Article and Find Full Text PDFObjectives/hypothesis: We aimed to determine the microRNA-21 expression in laryngeal squamous cell carcinoma and assess the association between the disease and clinical characteristics of patients.
Study Design: Retrospective case-control study.
Methods: A retrospective study was conducted from January 2005 to May 2011, in a tertiary hospital following tumor resection in 72 patients with laryngeal squamous cell carcinoma.
Laryngopharyngeal Reflux Has Negative Effects on Taste and Smell Functions.
Otolaryngol Head Neck Surg
July 2016
Objective: We evaluated the halimetric, olfactory, and taste functions of patients with laryngopharyngeal reflux (LPR).
Study Design: Prospective clinical study.
Setting: Multicenter tertiary care hospital.
Article Synopsis
- Subclinical hypothyroidism is linked to various health issues, but its effects on smell and taste functions are not well understood.
- A study involving 28 subclinical hypothyroid patients and 31 controls in Istanbul assessed their olfactory and gustatory functions before and after 3 months of L-thyroxine treatment.
- Results showed that patients had significantly lower scores in olfactory tests compared to controls, while the taste test indicated only a decreased sensitivity to bitter; however, there were improvements in smell functions after treatment, while taste improved specifically for bitter.
Background: Tumor necrosis factor-related associated-inducing ligand (TRAIL) is a death ligand currently under clinical trials for laryngeal carcinoma.
Methods: Paraffin-embedded tissues from 40 patients with laryngeal carcinoma and 20 patients with benign laryngeal pathologies were retrospectively analyzed using immunohistochemistry in terms of distribution and intensity, and for final analysis of immunoreactivity of receptors, H-score was used. The study group was assessed in terms of localization, lymph node staging, tumor stage, overall survival, disease-free survival, locoregional control, perineural invasion, and vascular invasion.