Comparison of Analgesic and Anti-Inflammatory Effects of Kale Extract Versus Ibuprofen After Impacted Mandibular Third Molar Surgery: A Randomized, Double-Blind Split-Mouth Clinical Trial.

Background/objective: We assessed the analgesic and anti-inflammatory effects of kale extract (500 mg anthocyanin equivalent) in patients after mandibular molar surgery.

Methods: In our randomized clinical trial, postoperative subjects (n = 20) aged 18-25 years old took kale extract or ibuprofen (400 mg) capsules for 7 days, or vice versa, after surgical removal of each impacted tooth. Their pain intensity was then assessed using a visual analogue scale (VAS).