Publications by authors named "Onofre J Martinez Madrid"
Brief Report: Patients' Experiences and Opinions After Desimplification of Their Single-Tablet Regimens for the Treatment of HIV Infection: A Survey in a Multicentre Cohort.
J Acquir Immune Defic Syndr
May 2022
Article Synopsis
- The study aimed to explore patient experiences and the effects of switching from a single-tablet regimen (STR) for HIV treatment to separate components on treatment adherence and quality of life.
- A survey was conducted among patients who transitioned from STRs to individual pills, revealing that most were aware of generic medications and generally supportive of the move to cut costs.
- While some patients reported issues with taking more pills and a decline in quality of life, the majority did not experience significant negative impacts on adherence or overall satisfaction with their treatment.
Introduction: In a previous interim 24-week virological safety analysis of the PROTEST study (1), initiation of Maraviroc (MVC) plus 2 nucleoside reverse-transcriptase inhibitors (NRTIs) in aviremic subjects based on genotypic tropism testing of proviral HIV-1 DNA was associated with low rates of virological failure. Here we present the final 48-week analysis of the study.
Methods: PROTEST was a phase 4, prospective, single-arm clinical trial (ID: NCT01378910) carried on in 24 HIV care centres in Spain.
Tuberculosis is a common infection worldwide. In developed countries, the incidence of this disease was low until a few years ago. However, due to the rise in immigration and HIV infection, the frequency of tuberculosis has recently shown a marked increase.
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