Assessment of cyclobutane pyrimidine dimers by digital photography in human skin.

UV-mediated DNA damage and repair are important mechanisms in research on UV-induced carcinogenesis. UV-induced DNA-damage and repair can be determined by immunohistochemical staining of photoproduct positive nuclei of keratinocytes in the epidermis. We developed a new method of analysing and quantifying thymine dimer (TT-CPD) positive cells in the epidermis.

Enteric-coated mycophenolate sodium versus cyclosporin A as long-term treatment in adult patients with severe atopic dermatitis: a randomized controlled trial.

Background: Cyclosporin A (CsA) is frequently used in the treatment of severe atopic dermatitis (AD). Enteric-coated mycophenolate sodium (EC-MPS) may be an alternative with equal efficacy and fewer side effects.

Objective: The aim of this observer-blinded randomized controlled trial was to compare EC-MPS with CsA as long-term treatment in adult patients with severe AD.

Photosensitivity testing in children.

Background: Phototesting is an important diagnostic tool to objectify light-related symptoms. Data on phototesting procedures in children are scarce.

Objective: The aim of this study was to evaluate phototest results in photosensitivity disorders in children.

Throwing a light on photosensitivity in atopic dermatitis: a retrospective study.

Background: Photosensitivity in atopic dermatitis (AD) is a well known but ill-defined phenomenon.

Objectives: To determine the prevalence of photosensitivity in patients with AD, define its clinical characteristics, and analyze the photo provocation test (phototest) results.

Methods: A retrospective study of patients with AD who were phototested because of suspected photosensitivity at our department during the period 1994-2004.