Synopsis of recent research by authors named "Onju Ham"
- Onju Ham's recent research primarily focuses on embryotoxicity assessments, utilizing advanced methodologies such as machine learning and high-throughput in vitro testing to identify predictive biomarkers and alternative assessment models for potential toxic substances.
- A significant finding from one study highlighted the role of multicollinearity in RNA-Seq data, leading to the identification of six genes linked to embryotoxicity, while another study developed a rapid, cost-effective mouse embryoid body model to evaluate toxicity efficiently.
- Additionally, Ham's research explores the impacts of compounds like Korean red ginseng extract and gut metabolites on developmental and aging-related phenotypes, thereby contributing to the understanding of safety profiles and disease models involving stem cells and organoids.