Optimizing Soil Stabilization with Chitosan: Investigating Acid Concentration, Temperature, and Long-Term Strength.

Civil and geotechnical researchers are searching for economical alternatives to replace traditional soil stabilizers such as cement, which have negative impacts on the environment. Chitosan biopolymer has shown its capacity to efficiently minimize soil erosion, reduce hydraulic conductivity, and adsorb heavy metals in soil that is contaminated. This research used unconfined compression strength (UCS) to investigate the impact of chitosan content, long-term strength assessment, acid concentration, and temperature on the improvement of soil strength.

Lack of correlation between school reopening and trends in adult COVID-19 hospitalisations and death rates during the Delta and early Omicron periods: An ecological analysis of five countries.

Objectives: In this ecological study, we describe SARS-CoV-2 case incidence and COVID-19 hospitalisation and death rates for school-aged and adult populations during the Delta and early Omicron periods, before and after schools reopened in five countries.

Methods: Data were extracted from government websites. Cases and COVID-19 hospitalisation and death incidence rates were calculated during the Delta and early Omicron periods in Australia, Canada, Denmark, Finland and the United Kingdom, for two weeks preceding and six weeks after schools reopened.

Endoscopic ultrasound with bronchoscope-guided transesophageal cryobiopsy: A case series with technical insights, key enablers, and review of literature.

Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is an established technique for lung cancer staging and the diagnosis of mediastinal diseases. Recently, the paradigm of EBUS guided mediastinal sampling with conventional cytology has shifted over to histology specimens through the use of cryobiopsy. This case series explores the novel technique, key enablers, and potential advantages of endoscopic ultrasound with bronchoscope-guided transesophageal cryobiopsy (EUS-B-TEC).

Federated learning as a smart tool for research on infectious diseases.

Background: The use of real-world data has become increasingly popular, also in the field of infectious disease (ID), particularly since the COVID-19 pandemic emerged. While much useful data for research is being collected, these data are generally stored across different sources. Privacy concerns limit the possibility to store the data centrally, thereby also limiting the possibility of fully leveraging the potential power of combined data.

Mesiodistal tip expression of mandibular anterior teeth in patients with mandibular incisor extraction treated with Invisalign aligners.

Introduction: Extraction of a single mandibular incisor may be prescribed in conjunction with clear aligner orthodontic treatment. The accuracy of therapeutic mesiodistal tooth positioning for the remaining mandibular anterior teeth for such patients has not been comprehensively evaluated. This retrospective study compared the predicted and achieved mesiodistal tooth movements in the mandibular anterior region for patients treated with Invisalign (Align Technology, Santa Clara, Calif), along with the influence of aligner attachments and the frequency of aligner change.

Associations between cognitive appraisals and emotions: A meta-analytic review.

The core premise of cognitive appraisal theories of emotion is that emotions are produced from our interpretation of what we experience. Compared to other major theoretical frameworks in emotion, the appraisal perspective emphasizes the centrality of these cognitive interpretations in giving rise to emotions. Decades of research have yielded numerous studies that broadly agree on the centrality of the appraisal process, but differ in the details, with different lists of appraisal dimensions, terminology, and only qualitative predictions for the relationship between select appraisals and emotions.

Rotavirus-Specific Maternal Serum Antibodies and Vaccine Responses to RV3-BB Rotavirus Vaccine Administered in a Neonatal or Infant Schedule in Malawi.

High titres of rotavirus-specific maternal antibodies may contribute to lower rotavirus vaccine efficacy in low- and middle-income countries (LMICs). RV3-BB vaccine (G3P[6]) is based on a neonatal rotavirus strain that replicates well in the newborn gut in the presence of breast milk. This study investigated the association between maternal serum antibodies and vaccine response in infants administered the RV3-BB vaccine.

Probabilistic programming versus meta-learning as models of cognition.

We summarize the recent progress made by probabilistic programming as a unifying formalism for the probabilistic, symbolic, and data-driven aspects of human cognition. We highlight differences with meta-learning in flexibility, statistical assumptions and inferences about cogniton. We suggest that the meta-learning approach could be further strengthened by considering Connectionist Bayesian approaches, rather than exclusively one or the other.

Emotion understanding as third-person appraisals: Integrating appraisal theories with developmental theories of emotion.

Emotion understanding goes beyond recognizing emotional displays-it also involves reasoning about how people's emotions are affected by their subjective evaluations of what they experienced. Inspired by work in adults on cognitive appraisal theories of emotion, we propose a framework that can guide systematic investigations of how an adult-like, sophisticated understanding of emotion develops from infancy to adulthood. We integrate basic concepts of appraisal theories with developmental theories of emotion understanding and suggest that over development, young children construct an intuitive, theory-like understanding of other people's emotions that is structurally similar to appraisal theories.

Transition metal Si-chalcogenides: a new two-dimensional anode material for Na-ion batteries.

Sodium (Na) ion batteries (SIB) hold great importance in energy storage due to their potential to offer a sustainable and cost-effective alternative to traditional lithium-ion batteries. Na is abundantly available and less expensive than lithium, making it an attractive option for large-scale energy storage applications. In the present work, we have predicted a series of 2D transition metal (TM) Si-chalcogenides (TMSiCs), TMXSi (TM = Ta, Nb and X = S, Se), which exhibit metallic characteristics.

An opportunity missed: Strengthening health system data on multisystem inflammatory syndrome in children from low- and middle-income countries in Asia.

Background: Multisystem inflammatory syndrome in children (MIS-C) is a severe complication associated with SARS-CoV-2 infection. The clinical epidemiology of MIS-C is not completely understood in low- and middle-income countries (LMICs) due to limited reporting, including in Asia where there was a substantial burden of COVID-19. We aimed to discuss the challenges of diagnosing MIS-C and factors which may cause children from Asian LMICs to have an increased risk of MIS-C.

Two decades of research trends in microbial-induced carbonate precipitation for heavy metal removal: a bibliometric review and literature review.

Amidst the increasing significance of innovative solutions for bioremediation of heavy metal removal, this paper offers a thorough bibliometric analysis of microbial-induced carbonate precipitation (MICP) for heavy metal removal, as a promising technology to tackle this urgent environmental issue. This study focused on articles published from 1999 to 2022 in the Scopus database. It assesses trends, participation, and key players within the MICP for heavy metal sequestration.

Epigenome-wide DNA Methylation Association Study of CHIP Provides Insight into Perturbed Gene Regulation.

With age, hematopoietic stem cells can acquire somatic mutations in leukemogenic genes that confer a proliferative advantage in a phenomenon termed "clonal hematopoiesis of indeterminate potential" (CHIP). How these mutations confer a proliferative advantage and result in increased risk for numerous age-related diseases remains poorly understood. We conducted a multiracial meta-analysis of epigenome-wide association studies (EWAS) of CHIP and its subtypes in four cohorts (N=8196) to elucidate the molecular mechanisms underlying CHIP and illuminate how these changes influence cardiovascular disease risk.

Fluorescein Angiogram Causing Cutaneous Venous Staining: A Rare Self-Resolving Phenomenon.

Introduction: Fluorescein angiography (FA) is a useful investigation in the diagnosis and treatment of retinal and choroidal disease. FA has well-reported adverse effects, most being mild. Very few cases have reported cutaneous venous staining following FA.

A holistic lifestyle mobile health intervention for the prevention of type 2 diabetes and common mental disorders in Asian women with a history of gestational diabetes: a randomised control trial with 3-year follow-up protocol.

Background: Women with a history of gestational diabetes mellitus (GDM) are 12-fold more likely to develop type 2 diabetes (T2D) 4-6 years after delivery than women without GDM. Similarly, GDM is associated with the development of common mental disorders (CMDs) (e.g.

Evaluating Dental Monitoring effectiveness compared with conventional monitoring of clear aligner therapy using the Peer Assessment Rating index.

Introduction: This study aimed to evaluate the effectiveness of Dental Monitoring (DM) (Dental Monitoring SAS, Paris, France) compared with conventional monitoring (CM) during active orthodontic treatment.

Methods: The Peer Assessment Rating (PAR) index was used to evaluate the pretreatment and posttreatment records of 51 patients, with 26 in the CM group and 25 in the DM group. The change in weighted PAR was analyzed to assess the effectiveness of treatment.

Conservative interdisciplinary management for a congenitally missing maxillary lateral incisor in an adolescent patient.

A congenitally missing lateral incisor tooth is commonly associated with both short and long-term clinical dilemmas, particularly for a growing patient. A unilaterally missing maxillary lateral incisor tooth creates a significant dental asymmetry in the critical aesthetic zone of the smile and potentially increases the difficulty of any subsequent orthodontic and restorative treatment. Carefully planned interdisciplinary management is required to address the challenges of anterior dental asymmetry, unilateral orthodontic space closure and to alleviate the concerns that accompany restorative implant placement in the anterior maxilla.

Clinical performance of predicting late age-related macular degeneration development using multimodal imaging.

Background: To examine whether the clinical performance of predicting late age-related macular degeneration (AMD) development is improved through using multimodal imaging (MMI) compared to using colour fundus photography (CFP) alone, and how this compares with a basic prediction model using well-established AMD risk factors.

Methods: Individuals with AMD in this study underwent MMI, including optical coherence tomography (OCT), fundus autofluorescence, near-infrared reflectance and CFP at baseline, and then at 6-monthly intervals for 3-years to determine MMI-defined late AMD development. Four retinal specialists independently assessed the likelihood that each eye at baseline would progress to MMI-defined late AMD over 3-years with CFP, and then with MMI.

PHF2 regulates genome topology and DNA replication in neural stem cells via cohesin.

Cohesin plays a crucial role in the organization of topologically-associated domains (TADs), which influence gene expression and DNA replication timing. Whether epigenetic regulators may affect TADs via cohesin to mediate DNA replication remains elusive. Here, we discover that the histone demethylase PHF2 associates with RAD21, a core subunit of cohesin, to regulate DNA replication in mouse neural stem cells (NSC).

Interdisciplinary management of an adolescent patient with a severely impacted mandibular canine.

Impacted mandibular canines often result in a variety of clinical dilemmas. Orthodontic disimpaction of severely displaced mandibular canines may be extremely challenging and associated with significant patient discomfort and a high risk of iatrogenic damage. This case report demonstrates the interdisciplinary management of a horizontally impacted permanent mandibular canine, utilising a combination of three-dimensional radiology, biomodel fabrication and subsequent endodontic treatment.