Intralesional epidermal growth factor for diabetic foot wounds: the first cases in Turkey.

Background: Intralesional recombinant epidermal growth factor (EGF) was produced in the Centre for Genetic Engineering and Biotechnology (CIGB), Cuba, in 1988 and licensed in 2006. Because it may accelerate wound healing, it is a potential new treatment option in patients with a diabetic foot wound (whether infected or not) as an adjunct to standard treatment (i.e.

Effects of two different solutions used in pin site care on the development of infection.

Objective: The aim of this study was to compare the effects of two different solutions used for pin site care in patients with external fixators on the incidence of pin site infection.

Methods: The study included 133 pins of 18 patients. The patient identification form, pin site care application form and the pin tract infection assessment form developed by Checketts et al.

Osteomyelitis or Charcot neuro-osteoarthropathy? Differentiating these disorders in diabetic patients with a foot problem.

Both osteomyelitis and Charcot neuro-osteoarthropathy (CN) are potentially limb-threatening complications of diabetic neuropathy, but they require quite different treatments. Almost all bone infections in the diabetic foot originate from an infected foot ulcer while diabetic osteoarthropathy is a non-infectious process in which peripheral neuropathy plays the critical role. Differentiating between diabetic foot osteomyelitis and CN requires careful evaluation of the patient, including the medical history, physical examination, selected laboratory findings, and imaging studies.

[Operative stabilization of traumatic flail chest using a reconstruction plaque].

Flail chest is the most serious form of blunt thoracic trauma that occurs as a result of fracture of three or more ribs from at least two places or sternal fractures and/or separation of costochondral junctions. Existence of life-threatening physiopathological changes almost always affects the clinical status of the patients. Typically the fractured segment moves in the interior and exterior directions during inspirations and expirations, respectively and this paradoxical motion is called as flail chest.

The diagnosis of diabetic foot osteomyelitis: examination findings and laboratory values.

Background: This study aimed to demonstrate how much examination findings and laboratory values can be helpful in the diagnosis of osteomyelitis in patients with diabetic foot infections.

Material/methods: Data of 46 consecutive inpatients prospectively followed up according to a specially designed "Diabetic Foot Follow-up Form" were analyzed. Following diagnostic interventions, clinical and laboratory findings of patients with and without a diagnosis of osteomyelitis were compared.

[Venous thromboembolism prophylaxis in major orthopaedic surgery: A multicenter, prospective, observational study].

Objectives: We investigated risk factors for venous thromboembolism (VTE), prophylaxis measures employed, and incidence of symptomatic deep venous thrombosis (DVT) and pulmonary embolism (PE) in patients undergoing major orthopaedic surgery (MOS).

Methods: An open, multicenter, prospective, observational study was conducted in 21 medical centers, comprising 899 patients. Of these, 316 patients (35.

[The microfracture technique in the treatment of full-thickness chondral lesions of the knee].

Objectives: Chondral lesions of the knee joint present a difficult challenge because of their poor potential for spontaneous healing. In this study, we evaluated the results of the microfracture technique in the treatment of full-thickness chondral lesions.

Methods: The study included 20 patients (12 males, 8 females; mean age 44 years; range 18 to 60 years) who were treated with the microfracture technique for 22 lesions of osteoarthritis or traumatic chondral injuries.

Transcutaneous electrical nerve stimulation offers partial relief in notalgia paresthetica patients with a relevant spinal pathology.

There is yet no established mode of curative treatment for notalgia paresthetica (NP). We had previously shown a correlation of NP localization with relevant spinal changes which led us to speculate on the possible role of spinal nerve impingement in the pathogenesis of this entity. Based on these findings we aimed to investigate the possible effect of physical therapy in selected cases of NP.

Reverse sural artery flap for distal lower extremity defects.

Traumatic and various dermatological conditions resulting in skin and subcutaneous tissue loss on the lower limb cause a therapeutic challenge for the dermatological surgeon, because this anatomical location lacks adequate skin laxity and has limited local soft tissue, especially around the heel. In this report, we present our experience with the reverse sural artery flap on seven patients. The soft tissue defect was traumatic in two patients.

Brown tumors mimicking bone metastases.

Brown tumors are rare skeletal manifestations of hyperparathyroidism (HPT) that may mimic cancer metastasis. Here, we present a 52-year-old woman with HPT and multiple foci of technetium uptake due to brown tumors on bone scintigraphy. Screening tests were negative for cancer and serum parathormon (PTH) measurement; parathyroid ultrasonography and scintigraphy suggested HPT.

The analgesic effect of nitroglycerin added to lidocaine on intravenous regional anesthesia.

We evaluated the analgesic effect of nitroglycerine (NTG) when added to lidocaine in IV regional anesthesia. Thirty patients undergoing hand surgery were randomly assigned to two groups. The control group (group C, n = 15) received a total dose of 40 mL with 3 mg/kg of lidocaine diluted with saline, and the NTG group (group NTG, n = 15) received an additional 200 mug NTG.

[In situ pinning on slipped femoral capital epiphysis with a single cannulated screw].

Background: Slipped femoral capital epiphysis requires immediate surgical intervention. Because this condition is relatively rare, the diagnosis is frequently delayed in patients with complaints of knee and hip pain and limping. Middle term results of patients who were diagnosed early and treated with a single cannulated screw are evaluated.

Investigation of spinal pathology in notalgia paresthetica.

A possible association of spinal pathology with notalgia paresthetica (NP) was investigated through clinical and radiographic evaluation. Forty-three NP patients underwent dermatologic and orthopedic examination accompanied by radiography of the spine. Sixty-one lesions in 43 patients were evaluated.

[Doxorubicin-induced chemomyectomy effects in rat skeletal muscle].

Objectives: This study was based on the assumption that decreased number of active muscle fibres in the spastic muscle may be associated with restoration of the balance. Hence, the effect of doxorubicin was evaluated in inducing permanent cell necrosis on skeletal muscle (chemomyectomy).

Methods: Eighteen Wistar rats were divided into two groups, equal in size, to receive doxorubicin injections (0.