Pseudomalignant myositis ossificans in the breast: A case report.

Myositis ossificans (MO) is characterized by abnormal heterotopic ossification formation, typically involving muscles, tendons, ligaments, fascia, and aponeurosis. It can be categorized into nonhereditary and hereditary types, with the latter being a distinct entity with a separate pathophysiology and treatment approach. The pathophysiology of MO formation remains to be fully elucidated.

Current possibilities of cervical precancerous lesions screening in Slovakia: prevalence of high risk human papillomavirus in patients with cytological diagnoses of atypical squamous cells of unknown significance.

Introduction: It has been confirmed, that there is a causal relationship between persistent infection of high risk human papillomavirus (HR-HPV) and the development of cervical cancer. In population of women older than 30 years HPV infection becomes a significant etiological factor of precancerous lesion of the cervix, but HPV infection may spontaneously regress in the majority of the cases.

Patients And Methods: The analysed study group consisted of 397 samples with cytological diagnosis of atypical squamous cells of unknown significance (ASCUS).

Renal oncocytoma with invasive histopathologic features - case report.

Background: Renal oncocytoma is an uncommon tumor, classified as a benign renal neoplasm in the World Health Organisation classification of renal tumours. Despite it there were described several reports with invasive histopathologic features.

Case Report: We describe a case of renal oncocytoma with bizzare cells and invasion of renal sinus fat tissue.

Perineural cell differentiation in ganglioneuromas. Report of 8 cases with immunohistochemical expression of perineural cell markers.

Eight cases of ganglioneuroma were examined for a presence of perineural cell differentiation, using the immunohistochemical markers epithelial membrane antigen (EMA), claudin-1 and GLUT-1. The mean age of the patients was 42.3 years (range 26-68 years), six patients were females and two were males.

Mediastinal ganglioneuroma with perineural cell differentiation. Report of a case.

An unusual case of ganglioneuroma with perineural cell differentiation is presented. The tumor was removed from the mediastinum in a 34-year-old male patient. Histologically, it contained neuroid bundles of bland spindle cells, scattered ganglion cells, and some foci of adipocytic metaplasia.

FDG-PET in the Erdheim-Chester disease: its diagnostic and follow-up role.

A 62-year-old man presented with diabetes insipidus, pulmonary fibrosis, right atrial tumor and bilateral knee osteoarthritis with cystic lesions of distal femur and proximal tibia. Scintigraphy and histological examination of right femur bone biopsy revealed changes characterized for Paget's disease. Re-evaluation of the computer tomography (CT) scans and histological samples revealed diffuse infiltrates of foamy histiocytes in the bone marrow what was consistent with Erdheim-Chester disease.

[Acute cholestasis following treatment with nimesulide and oral contraception: case report and review].

Our case report of acute cholestatic liver injury highlights the potential hepatotoxicity of nimesulide treatment in combination with oral contraception. Rarely occuring histological findings of "pure" cholestasis without any inflammatory or necrotic changes with favourable outcome following ursodeoxycholic acid administration are described. It was not possible to distinguish the separate role of any of these two drugs on hepatotoxicity according to the available information.

[Intraductal papillary proliferation of brest. Actual review and clinicopathological corelation].

Objective: Complex summary addressing current view of the intraductal papillary lesions of breast, especially focused on morphology, exact terminology and clinicopathological aspects of effective therapy.

Design: Review article.

Setting: Biopsy Lab s.

[Giant retroperitoneal liposarcomas].

According to literature liposarcomas account to less than 0.1% of all human tumors, 13% of which are localiced retroperitoneally. Authors describe two cases of giant retroperitoneal liposarcoms treated in their department.

Polythelia is not a mere aesthetic issue.

Anomalies in breast development include an increase in the number of breast (polymastia), nipples (polythelia), areolas (polythelia areolaris) and the tissue of the breast gland. Of the many forms, the most common is an accessory nipple, polythelia. It commonly develops along the embryonic "milk line" (Fig.

[Pathologic findings in the uterine cervix--diagnostic aspects].

The study presents results of routine bioptic diagnoses. 651 lesions of cervix uteri have been diagnosed during a five-year period. The presented number represented a summary of 26% of the absolute number of 2513 registered neoplastic and precancerous lesions of the female genital.

Desmoplastic cellular blue nevi.

We describe five cases of cellular blue nevus (CBN) accompanied by an abundant desmoplastic reaction. The cells within the desmoplastic regions reacted strongly immunohistochemically with antibodies to S-100 protein and HMB-45 and were negative to antibodies to smooth muscle actin and desmin, providing evidence that the abundant collagen deposits were the product of the nevus cells. The microscopic picture of desmoplastic CBN can differ considerably from that of common CBN, and differential diagnosis is discussed.

[Retrorectal and presacral tumors].

The group of patients with retrorectal and presacral tumours is presented. Their clinical picture, CT examination, results of biopsy and surgery treatment are analysed. The authors present the recent procedures of diagnosis and therapy of tumors in this location.

[Morphologic findings in models of acute experimental pancreatitis].

Morphological changes found in two models of acute experimental pancreatitis are presented. Acute pancreatitis was induced in rats by the method of ligation of the lateral pancreatic ducts and by the method of the blind duodenal loop. After four hours the animals were sacrificed and processed for light and electron microscopic examination.

[Precancerous and malignant tumors of the uterine cervix].

Bioptic findings recorded in 366 women with lesions of the endocervix and exocervix were analyzed in a retrospective study covering the years 1988 to 1990. The series represented 24.5% of the total number of 1495 gynecological precancerous and tumorous changes.

[Pathology of the uterine cervix. Infectious lesions of the endocervix and exocervix].

Bioptic findings from the region of the endo- and exocervix of the uterus were analyzed in a retrospective study covering the years 1988-1990. The series studied consisted of 366 women. Infectious processes in the cervix were evaluated in this first part of the study.

[Microscopic diagnosis of mixed and mesenchymal tumors of the mucosa and uterine body].

A series of 452 with 831 precancerous and tumorous lesions of the corpus uteri is presented. The series was obtained by analyzing the authors' own series of bioptic findings covering the period of two years. Some problems arising at the evaluation of proliferating myogenic and stromal precancerous and tumorous lesions are pointed out.

Mixed hepatoblastoma in the adult: morphological and immunohistochemical findings.

A case of mixed hepatoblastoma in a 66-year-old man is discussed. Assessment of malignant mesenchymal and malignant epithelial elements yields the diagnosis. In the reported case, the epithelial area consisted of fetal hepatocytes.