Publications by authors named "Ondine Strachowski"
Introduction: The combined use of intraoperative MRI and awake surgery is a tailored microsurgical resection to respect functional neural networks (mainly the language and motor ones). Intraoperative MRI has been classically considered to increase the extent of resection for gliomas, thereby reducing neurological deficits. Herein, we evaluated the combined technique of awake microsurgical resection and intraoperative MRI for primary brain tumours (gliomas, metastasis) and epilepsy (cortical dysplasia, non-lesional, cavernomas).
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- - The text discusses a case of a 27-year-old male patient who underwent awake surgery for a cavernous malformation in a sensitive brain area that caused hemorrhage and epilepsy, using advanced imaging techniques.
- - The surgery involved a combination of preoperative diffusion tensor imaging, neuronavigation, and intraoperative MRI to successfully remove the malformation, despite patient movement during the procedure.
- - Post-surgery, the patient experienced a single seizure but showed no significant complications, and follow-up imaging confirmed complete removal of the malformation with normal cognitive function reported in neuropsychological tests.
Microsurgical resection of primary brain tumors located within or near eloquent areas is challenging. Primary aim is to preserve neurological function, while maximizing the extent of resection (EOR), to optimize long-term neurooncological outcomes and quality of life. Here, we review the combined integration of awake craniotomy and intraoperative MRI (IoMRI) for primary brain tumors, due to their multiple challenges.
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