Critical appraisal of the "one-day-per-percent" rule - A register-based observational study.

Background: The "one-day-per-percent" rule states that for burn patients, one day of hospital stay can be expected for each percentage of burned body surface. This study aimed to test the rule's predictive value.

Methods: The study is a register-based observational study on all burns treated in the Norwegian National Burn Center 2000-22.

Patients over 75 years admitted to the National Burn Centre, Haukeland University Hospital, 2000-19.

Background: The number of burn patients over the age of 75 receiving advanced treatment, including extensive surgery and intensive care, is increasing. We aimed to describe the treatment and outcomes for burn patients over the age of 75 admitted to the National Burn Centre at Haukeland University Hospital. We also wanted to investigate whether frailty scores can be a predictor of the treatment outcome.

Vasoactive and/or inotropic drugs in initial resuscitation of burn injuries: A systematic review.

Background: According to current guidelines, initial burn resuscitation should be performed with fluids alone. The aims of the study were to review the frequency of use of vasoactive and/or inotropic drugs in initial burn resuscitation, and assess the benefits and harms of adding such drugs to fluids.

Methods: A systematic literature search was conducted in PubMed, Embase, Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials, UpToDate, and SveMed+ through 3 December 2021.

Patients with burn injuries admitted to Norwegian hospitals - a population-based study.

Background: The objective of this article is to elucidate the scope of burn injuries in Norway, on the basis of those patients who had sustained a burn injury that caused hospitalisation through a calendar year.

Material And Method: The article is based on data retrieved from the Norwegian Patient Registry on patients discharged from Norwegian hospitals in 2012 with a burn injury as their main diagnosis, supplemented with activity data for children admitted to the Burn Unit, Haukeland University Hospital, Bergen, during the period 2013 – 15.

Results: In 2012, altogether 620 people (12.

[Treatment of serious burns].

Background: Treatment of patients with large burns is challenging.

Material And Method: The article is based on clinical experience, and a non-systematic review in PubMed.

Results: In patients with burns covering more than 10 - 15 % of the total body surface area, fluid resuscitation should be initiated early.

The epidemiology of patients with burn injuries admitted to Norwegian hospitals in 2007.

Objectives: To study the incidence and outcome of burns in Norway in 2007, and to establish estimates for effective length of stay, mortality and economical costs.

Methods: Data from the Norwegian Patient Registry on all patients discharged from all somatic hospitals in Norway in 2007 with main or subsidiary diagnosis of burn injury (ICD-10: T20-31) were collected.

Results: Seven hundred and twenty-six patients (65.

[Burn treated at the Haukeland University Hospital Burn Centre--20 years of experience].

Background: The Burn Centre at Haukeland University Hospital has had a national burn function since 1984.

Patients And Methods: The following data were reviewed: area injured, age, sex, length of stay, mortality and county of residence for all admissions in the period 1984-2004.

Results: 1294 acute admissions for burns, chemical injuries or high-voltage injuries were identified.

Fluid shift is moderate and short-lived during acute crystalloid hemodilution and normothermic cardiopulmonary bypass in piglets.

Background: Crystalloids are commonly used as priming solutions during cardiopulmonary bypass (CPB). Consequently, hemodilution is a regular occurrence at the start of a CPB. This study describes the time-course variations of hemodynamic parameters, plasma volume (PV) and fluid exchange following crystalloid hemodilution at start of normothermic CPB.

Time course variations of haemodynamics, plasma volume and microvascular fluid exchange following surface cooling: an experimental approach to accidental hypothermia.

Objective: To describe how surface cooling influences fluid distribution, vascular capacity and haemodynamic variables.

Methods: Seven anaesthetised pigs, following normothermic stabilization for 60 min, were cooled to 27.8+/-1.

High risk for accidental death in previously burn-injured adults.

This study investigated the long-term mortality in 1182 burn patients admitted at a single burn centre in 1984-2003. One thousand and forty-nine patients were discharged alive, of which 999 (95.2% of all discharged) were available for follow-up (mean observation time: 9.

[Hospital admissions for burns].

Background: We wanted to investigate the incidence of burns and the volume of in-hospital burn treatment in Norway.

Material And Methods: Data for 1999 were compiled from hospital admissions as reported to the Norwegian Patient Register. Selection was based on ICD-10 codes for burns, though caustic injuries, reconstructive procedures, and patients discharged alive with length-of-stay less than 1 day were not included.

Porcine surfactant (Curosurf) for acute respiratory failure after near-drowning in 12 year old.

This case report describes rapid and persistent improvement after one single dose of porcine surfactant (Curosurf) 0.5 ml/kg(-1) (40 mg/kg) intratracheally for adult respiratory distress syndrome (ARDS) with severe oxygenation failure 8 h after freshwater near-drowning in a 12-year-old girl.

Can the use of methylprednisolone, vitamin C, or alpha-trinositol prevent cold-induced fluid extravasation during cardiopulmonary bypass in piglets?

Objective: Hypothermic cardiopulmonary bypass is associated with capillary fluid leakage, resulting in edema and occasionally organ dysfunction. Systemic inflammatory activation is considered responsible. In some studies methylprednisolone has reduced the weight gain during cardiopulmonary bypass.

Outcome after acute respiratory failure is more dependent on dysfunction in other vital organs than on the severity of the respiratory failure.

Introduction: The incidence and outcome of acute respiratory failure (ARF) depend on dysfunction in other organs. As a result, reported mortality in patients with ARF is derived from a mixed group of patients with different degrees of multiorgan failure. The main goal of the present study was to investigate patient outcome in single organ ARF.

[Outbreak of multiresistant Acinetobacter baumannii infection].

Background: Nosocomial infections caused by multiresistant gram-negative bacteria represent an increasing problem, especially among intensive care patients. A serious outbreak of infection caused by multi-resistant Acinetobacter baumannii occurred in four burn patients. Acinetobacter is a gram-negative coccibacilli which is widespread in nature, and has been reported as an increasing problem in critically ill patients.

Markedly increased lymphatic removal of hyaluronan from skin after major thermal injury.

Hyaluronam (HYA) (formerly hyaluronic acid) is an important constituent of the interstitial matrix in skin. Following major burn injury plasma HYA is known to increase markedly. The present study investigated to what extent the lymphatic removal of HYA from skin is affected following major burn injuries.

Retention and distribution of polygeline (Haemaccel) in the rat.

The plasma substitute polygeline (Haemaccel registered) contains a large fraction of molecules sufficiently small to cross the capillary and glomerular membranes. Plasma volume expansion, tissue extravasation and renal elimination of this artificial colloid were quantified using 125I-labelled polygeline molecules. In pentobarbital anaesthetized rats, either 10 ml 3.

Fluid shifts following 7% hypertonic saline (2400 mosmol/L) infusion.

Small volumes of hyperosmolar saline solutions may rapidly improve MAP and CO in hemorrhagic shock. In the present study, the effects of infusion of 7% NaCl on interstitial fluid volume and intracellular fluid volume were determined. In anesthetized, normovolemic rats either 7% NaCl (1.

[Patients with burns admitted to hospitals in 1992. Fewer cases and shorter length of stay also in Norway?].

Patients admitted for care of acute burns in Norway in 1992 were compared with patients in an earlier national survey in 1977. In 1992, 635 patients were admitted for acute burns in Norway, 20% less than in 1977. 8,975 hospital days were spent on care of acute burns, a 45% reduction compared with 1977.

Increased plasma concentrations of hyaluronan after major thermal injury in the rat.

Hyaluronan (HYA) is an ubiquitous polysaccharide in connective tissue interstitium; its normal plasma concentration is in the nanogram/ml range. Following major burn injury in sheep, plasma HYA can increase to levels tenfold greater than normal. The present study aimed to determine the effects of major cutaneous burns on plasma HYA concentration in rat, since in this species, the HYA elimination kinetics may better resemble those in man.

Pathogenesis of edema formation in burn injuries.

One of the obvious acute features of cutaneous thermal injury is the swelling of the involved tissue. This swelling is caused by a fluid shift from circulating plasma. Along with the evolution of intravenous fluid therapy in trauma and surgery, the implementation of such therapy to burn victims has improved survival.