Publications by authors named "Omou Bah Sow"
N Engl J Med
October 2014
Article Synopsis
- A phase 3 trial aimed to shorten tuberculosis treatment by testing a 4-month regimen with gatifloxacin against a standard 6-month regimen including ethambutol, focusing on patients with rifampin-sensitive pulmonary TB in sub-Saharan Africa.
- The study involved 1836 patients and evaluated the frequency of unfavorable outcomes, like treatment failure or death, 24 months post-treatment, finding a 3.5 percentage point higher risk in the 4-month group compared to the standard regimen.
- Results showed variability among different countries, indicating that the effectiveness of the treatment may differ based on local factors such as baseline health status and body mass index.
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