Publications by authors named "Omoerere Oborirhovo"
Characterization, Anti-glycation, Anti-inflammation, and Lipase Inhibitory Properties of Rauvolfia vomitoria Leaf Extract: In Vitro and In Silico Evaluations for Obesity Treatment.
Akpovwehwee A Anigboro Oghenetega J Avwioroko Omoerere Oborirhovo Onoriode Akeghware Ernest U Durugbo
Appl Biochem Biotechnol
October 2024
Article Synopsis
- Pancreatic lipase (PLP) is an enzyme that breaks down fats, and inhibiting it could help manage obesity, leading to research on safer natural inhibitors due to side effects from traditional ones.
- The study tested the effects of extracts from Rauvolfia vomitoria leaves (aqueous, ethanolic, and methanolic) on anti-glycation, anti-inflammatory, and lipase inhibition using lab techniques to analyze the compounds' properties.
- Among the extracts, the methanolic one (MRV) showed the strongest PLP inhibition and interacted effectively with the enzyme, suggesting potential for a natural obesity treatment and insights into drug design.