Implication of caffeine consumption and recovery on the reproductive functions of adult male Wistar rats.

Background: This study assessed the impact of caffeine consumption and recovery on reproductive functions and fertility of Wistar rats.

Methods: Thirty-five adult male Wistar rats were divided into seven groups of five rats each. Group A (control) received distilled water (vehicle), while groups B, C, and D were treated orally with 10 mg/kg body weight (BW), 20 mg/kg BW, and 40 mg/kg BW caffeine, respectively, for 30 days.

Effects of Oral Maternal Administration of Caffeine on Reproductive Functions of Male Offspring of Wistar Rats.

Caffeine was investigated for its possible fetal programming effects on reproductive function of male offspring. Sixty-five pregnant Wistar rats were grouped into four. Group 1 was control and received distilled water.