Publications by authors named "Omnia Mohamed Abdel Maksoud"
Article Synopsis
- * The study involved seven groups of rats, including various control and treatment groups, to assess the impact of these compounds on mitochondrial proteins, renin-angiotensin system activity, ATP levels, and Na-K ATPase gene expression.
- * Findings revealed that resveratrol, L-carnitine, and apelin positively influenced mitochondrial quality control and improved kidney function by modifying specific proteins and enhancing energy production in the renal tissue.
Aim: High cholesterol diet is greatly linked to deleterious health consequences. In this work we tried to explore direct effects of high cholesterol diet on striated (skeletal and cardiac) muscle tissues and the mechanisms by which nebivolol could improve such harmful effects.
Methods: The study included 24 healthy adult male albino rats weighing 200-220 grams that were assigned into four groups: control group, control drug group, high cholesterol diet fed groups; one untreated the other was treated with nebivolol.
Aim: An experimental study of the effect of two vasodilators, carvedilol (B blocker with alpha-antagonist) and nicorandil (NO donor) on nonalcoholic fatty liver (NAFLD) induced by hypercholesterolemia and fatty diet in rats through studying the possible anti-inflammatory and antioxidant mechanisms.
Main Methods: The rats were divided into 4 groups (6 rats each): The first (negative control group). The second, third and fourth groups were fed with cholesterol and fat- enriched diet for one month that stopped and continued on the standard diet for another month without treatment in the second group but treated with carvedilol and nicorandil in the third and fourth group respectively.