Publications by authors named "Omnia A El-Dydamoni"
This study examined the genotype, allelic frequencies (polymorphisms) in a sample of Egyptian patients and examined the relationship between disease activity in systemic lupus erythematosus (SLE) and the B lymphoid tyrosine kinase (BLK) and B-cell scaffold protein with ankyrin repeats 1 (BANK1) gene. This case control study involved 70 SLE patients and 40 subjects matched for age and sex as a control group. Clinical data were gathered from each participant, including SLE-related clinical activity indicators.
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- * Results showed that 11% of donors tested positive for T. gondii antibodies, while low HIV, HBV, and HCV infection rates were observed, with no cases of syphilis.
- * Identified risk factors for T. gondii infection included being female, eating raw meat, living in agricultural areas, lack of awareness, and certain blood types, pointing to the need for improved education and preventive measures.
Background: Immune dysregulation plays an important role in the pathogenesis of rheumatoid arthritis (RA). The CD4+CD25 high FoxP3+ subset of regulatory T cells plays an essential role in preventing autoimmunity and maintaining immune homeostasis. Negative regulation of JAK/STAT signaling is controlled by Suppressor of Cytokine Signaling (SOCs3) proteins.
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