Publications by Omkulthom M Alkamaly

Publications by authors named "Omkulthom M Alkamaly"

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Dual EGFR/VEGFR2 inhibitors and apoptosis inducers: Synthesis and antitumor activity of novel pyrazoline derivatives.

Omkulthom M Alkamaly Najla Altwaijry Rehab Sabour Marwa F Harras

Arch Pharm (Weinheim)

April 2021

Novel derivatives of the pyrazoline scaffold were synthesized and investigated for their cytotoxicity against prostate (PC-3), hepatocellular (HepG2), and breast (MDA-MB-231) carcinoma cells. The most active compounds, 4a, 4b, 5b, and 7c, revealed significant and broad-spectrum anticancer activities with IC values of 1.30-7.

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