Clinical pharmacokinetics of the diastereomers of arteether in healthy volunteers.

Objective: To evaluate the pharmacokinetics of alpha- and beta-diastereomers of arteether in healthy male volunteers.

Participants And Methods: The study was a single-centre clinical pharmacokinetic trial in healthy male subjects. A group comprising 13 subjects aged 25-50 years received a single intramuscular 150 mg individual dose of the arteether formulation containing alpha- and beta-isomers in a 30:70 ratio.