Anti-inflammatory, cytotoxic and morphological impact of phycocyanin on ultraviolet radiation irradiated human fibroblast cells.

Background: Recently, the use of natural products as skin photoprotective agents has been in increasing demand. This study investigated the bioactivity of phycocyanin (PC) extracted from sp. on human skin fibroblast cell line (CCD-966SK), specifically focusing on apoptosis, necrosis, anti-inflammatory effects, and enzymatic reactions.