Interleukins (ILs) play a significant role in triggering the inflammatory response in blood vessels and immune cells. A systematic review and meta-analysis were conducted to investigate the relationship between IL-8 (rs4073), IL-13 (rs1800925), IL-22 (rs1179251, rs1179246, and rs2227485), and IL-27 (rs17855750 and rs153109) polymorphisms and the risk of developing colorectal cancer (CRC). Four databases were searched up until October 13, 2023, without any restrictions, to find relevant studies.
View Article and Find Full Text PDFObjective: Psoriasis is a disease with an immunogenetic background in which cytokines have important effects on its prevalence and incidence. The present meta-analysis evaluated the relationship between () polymorphisms (, , , , and ) and psoriasis risk in studies following Hardy-Weinberg equilibrium (HWE).
Materials And Methods: Four databases were searched to retrieve relevant studies reporting the distributions of polymorphisms in psoriasis cases compared to controls.
The aim of this study was to analyze the single and combined effects of -acetyl cysteine (NAC) and doxycycline (Dox) on the inflammatory and angiogenic factors in the rat model of alkali-burned cornea. Rats were treated with a single and combined 0.5% NAC and 12.
View Article and Find Full Text PDFAim Of The Study: We reported the association between interleukin 8 () polymorphisms (251T/A and 781C/T) and hepatocellular carcinoma (HCC) risk in a meta-analysis.
Material And Methods: Scopus, PubMed, Web of Science, and Cochrane Library databases were searched until 21 November 2020. The analyses were performed by RevMan 5.
Aim Of The Study: We reported the association between interleukin 6 polymorphisms (rs1800796, rs1800795, rs2069837, rs17147230, and rs1800797) and hepatocellular carcinoma (HCC) susceptibility in a meta-analysis.
Material And Methods: The studies were retrieved by searching the search terms in Scopus, PubMed, Web of Science, and Cochrane Library databases until June 2020. The analyses were done by RevMan 5.