Background: Pancreatic neoplasm is one of the types of cancer with a high incidence and case-fatality rate.
Objectives: This study was designed to investigate the relationship between statin intake and the risk of pancreatic cancer with a systematic review and meta-analysis approach.
Methods: This study was a systematic review and meta-analysis of studies published before 2023 in Cochrane Library, Web of Science (WOS), PubMed, Google Scholar, ScienceDirect, Scopus, and Embase databases.
Background: Ischemia-reperfusion injury (IRI) is a well-known ailment that can disturb organ function.
Objectives: This systematic review study investigated fisetin's effects and possible mechanisms in attenuating myocardial, cerebral, renal, and hepatic IRIs.
Methods: This systematic review included studies earlier than Sep 2023 by following the PRISMA statement 2020.
Recent Pat Anticancer Drug Discov
January 2024
Background: Hepatocellular Carcinoma (HCC) is a public health problem around the world. Several studies have investigated the association between statin use and the risk of HCC, however, more studies are needed in this field.
Objectives: This systematic review and meta-analysis aimed to investigate the relationship between statin use and HCC risk.
Thyroid follicular dendritic cell sarcoma (FDCS) is an extremely rare malignancy that originates from follicular dendritic cells of the thyroid germinal centers. To the best of our knowledge, there are only 4 reported cases of thyroid FDCS in the English literature. Herein, we present the fifth case of FDCS of the thyroid gland.
View Article and Find Full Text PDFIntroduction And Importance: Synovial cell sarcoma (SS) is an extremely rare mesenchymal malignancy, representing nearly 10% of all soft-tissue sarcomas. These high-grade soft tissue sarcomas commonly arise in the para-articular regions of lower extremities. However, 15% of Synovial sarcomas has been described at Unusual locations, including head, neck, and trunk.
View Article and Find Full Text PDFBackground: Hepatitis B virus is one of the transfusion transmissible infections. Despite the availability of hepatitis B virus (HBV) vaccine and screening tests but still danger of virus transmission via blood transfusion is high in some regions. The objective of this study was to determine the trend of seroprevalence of hepatitis B in over an 11-year period (2005-2015).
View Article and Find Full Text PDFMutations in the CDC14A (Cell Division-Cycle 14A) gene, which encodes a conserved dual-specificity protein tyrosine phosphatase, have been identified as a cause of autosomal recessive non-syndromic hearing loss (DFNB32) and hearing impairment infertility male syndrome (HIIMS). We used next-generation sequencing to screen six deaf probands from six families segregating sensorineural moderate-to-profound hearing loss. Data analysis and variant prioritization were completed using a custom bioinformatics pipeline.
View Article and Find Full Text PDFInt J Pediatr Otorhinolaryngol
January 2018
Introduction: Autosomal recessive cerebellar ataxias (ARCAs) are a large group of neurodegenerative disorders that manifest mainly in children and young adults. Most ARCAs are heterogeneous with respect to age at onset, severity of disease progression, and frequency of extracerebellar and systemic signs.
Methods: The phenotype of a consanguineous Iranian family was characterized using clinical testing and pedigree analysis.
Aim: The aim of this study was to evaluate the relationship between age and cell adhesion molecule markers (E-cadherin and syndecan-1).
Materials And Methods: Forty-three cases of gastric carcinoma below the age of 50 were referred to our center in the period of 5 years (2003–2008). Forty-three gastric carcinoma above the age of 50 years were sex-matched with the first group.