Outcomes of minimally invasive surgery for pulmonary metastasis: who benefits the most?

Introduction: Metastatic disease is one of the main causes of death and factors affecting overall survival. It is known that selected patients with pulmonary oligometastases whose primary tumor is under control and who have adequate respiratory capacity may benefit from metastasectomy by resecting all detected lesions.

Aim: To report our findings on the use of video-assisted thoracoscopic surgery (VATS) for pulmonary metastasectomy, with a focus on identifying suitable candidates.

Post bar removal results of pectus deformity patients who underwent minimally invasive correction.

Introduction: The most common chest wall deformities are pectus excavatum and pectus carinatum. Surgical repair of these deformities via minimally invasive technique using pectus bars is commonly preferred by numerous thoracic surgeons. Despite this common choice for treatment, the duration of the bar stay, the bar removal process, the possible complications and ways to prevent them have been debated over the years and still there is no single decision.

Mediastinal lymph node removal modulates natural killer cell exhaustion in patients with non-small cell lung cancer.

Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death globally. In this study, the effect of complete removal of mediastinal lymph nodes by video-assisted mediastinoscopic lymphadenectomy (VAMLA) on natural killer (NK) cell phenotype and functions in patients with NSCLC was evaluated. The study included 21 NSCLC patients (cIA-IVA) undergoing VAMLA staging and 33 healthy controls.

Mediastinal lymph node removal ameliorates cytotoxic T-lymphocyte functions in patients with non-small cell lung cancer.

Introduction: Mediastinal lymph node (MLN) removal by video-assisted mediastinoscopic lymphadenectomy (VAMLA) for preoperative cancer staging was reported to be associated with increased survival. The aim of this study was to evaluate the immunologic effects of complete MLN removal by VAMLA on cytotoxic T lymphocyte (CTL) phenotype and function.

Methods: Seventeen patients with non-small cell lung cancer (NSCLC) (stage cT1-4N0-3M0-1A) and 20 healthy participants were included in this study.

Laryngopharyngeal Reflux Has Negative Effects on Taste and Smell Functions.

Objective: We evaluated the halimetric, olfactory, and taste functions of patients with laryngopharyngeal reflux (LPR).

Study Design: Prospective clinical study.

Setting: Multicenter tertiary care hospital.

Olfactory and Gustatory Functions after Anterior Palatoplasty in Patients with Primary Snoring.

Objective: In this study, we investigated the chemical senses (namely, olfaction), the 4 basic tastes, and umami taste in patients who underwent anterior palatoplasty (AP) for primary snoring.

Study Design: Prospective clinical study.

Setting: Multicenter, tertiary care hospitals.

Cross-culturally modified University of Pennsylvania Smell Identification Test for a Turkish population.

Background: The University of Pennsylvania Smell Identification Test (UPSIT) is a well-developed and popular olfactory test, which has been validated in various populations. However, there was only one study in a Turkish population, and this study indicated that the North American version of the UPSIT was not enough to evaluate the olfactory functions of Turkish population. So, we developed a cross-cultural adaptation of the UPSIT, the UPSIT-Turkish (UPSIT-T).

Olfactory and gustatory dysfunction in Myasthenia gravis: A study in Turkish patients.

Objective: Myasthenia gravis (MG) is commonly viewed as a muscle disorder. Less is known about neurosensory function and dysfunction in MG. We aim to evaluate olfactory and gustatory behavior in Turkish patients with MG, and compare these results with age and sex-matched healthy controls.

Modified olfactory training in patients with postinfectious olfactory loss.

Objectives/hypothesis: Patients with olfactory dysfunction benefit from repeated exposure to odors, so-called olfactory training (OT). This does not mean occasional smelling but the structured sniffing of a defined set of odors, twice daily, for a period of 4 months or longer. In this prospective study, we investigated whether the effect of OT might increase through the use of more odors and extension of the training period.

Sudden hearing loss associated with methylphenidate therapy.

An 8-year-old child diagnosed with attention deficit/hyperactivity disorder presented to our Department of Otolaryngology 4 days after suffering hearing loss, loss of balance, tinnitus, and fullness sensation of the left ear. Her symptoms occured with the first dose of methylphenidate. The medical history and physical examination revealed no other diseases associated with sudden hearing loss.

Leiomyosarcoma of the soft palate.

Tumors of the smooth muscles are rarely seen, as the number of smooth muscles is low within the intraoral region. Leiomyosarcoma is a type of malign tumor originating from smooth muscles. The most common regions of leiomyosarcoma of the oral cavity are the maxilla and mandible.

The course of the marginal mandibular branch of the facial nerve in adult cadavers. An anatomic study.

Objective: To observe the course of the marginal mandibular branch of the facial nerve (MMBFN) and its relation to the inferior border of the mandible and facial vessels.

Methods: This cadaveric study was conducted at the Department of Anatomy, Gulhane Military Medical Academy, Ankara, Turkey from April to September 2012. The 44 facial halves of 22 adult cadavers were dissected under a stereomicroscope.

Z-shaped asymmetric hump resection and unilateral osteotomy for treatment of deviated noses.

Numerous techniques have been described to correct deviated nose deformities. This article discussed the Z-shaped asymmetric hump resection combined with unilateral osteotomy. Fifty-eight cases that we operated between 2003 and 2009 for deviated nose deformity were included in the study.

CT and MRI of an unusual intranasal mass: pleomorphic adenoma.

A rare case of pleomorphic adenoma arising from the nasal septum is presented. Computed tomography (CT) and magnetic resonance imaging (MRI) of a 65- year-old woman who presented with right sided nasal obstruction, nasal discharge and epistaxis revealed a well-defined lobular mass occupying the right nasal cavity. Histopathologic examination revealed a pleomorphic adenoma.

Effective dose of 5-fluorouracil for myringotomy in rats.

Background: The purpose of this study is to compare the effects of two different doses of 5-fluorouracil (5-FU) on closure rates and histopathological findings in myringotomy to those of simple myringotomy with saline application.

Material/methods: 36 rats were divided into two study groups and a control group of 12 rats each. After bilateral myringotomy, we applied 5-FU 50 mg/ml in group A, 10 mg/ml in group B and saline in the control group for 10 minutes.

Effects of topical application of mitomycin-C and 5-fluorouracil on myringotomy in rats.

Objective: The effects of topical application of Mitomycin-C (MMC) and 5-fluorouracil (5-FU) for maintaining myringotomy patency were investigated in this experimental study.

Study Design: We performed simple myringotomy with a knife on 140 tympanic membranes of 70 rats. Rats were divided in two study groups and a control group.

Mastoid osteomas: report of two cases.

Objective: To discuss the differential diagnosis of two cases with mastoid mass.

Study Design: Case report and review of the literature.

Setting: The study was carried out in Gulhane Military Medical Academy, Haydarpasa Training Hospital, Istanbul, Turkey.