Publications by authors named "Omer Karadas"
Objective: Numerous studies have been conducted investigating the effects of antiseizure medications (ASMs) on cognitive functions, and the cognitive side effects of some ASMs have been demonstrated. However, data on whether tolerance to these side effects develops over time is insufficient. The aim of this study is to evaluate the reversibility of cognitive impairments caused by ASMs in patients, utilizing event-related potentials (ERPs) and the Montreal Cognitive Assessment (MoCA) test.
View Article and Find Full Text PDFBackground: Variable incidence and prevalence rates of myasthenia gravis (MG) have been reported over time from different geographical regions. We aimed to determine incidence and prevalence of MG in Turkey and contribute to the development of proper national health policies.
Methods: Patients with G70.
Article Synopsis
- The study aimed to investigate how antiseizure medications (ASMs) affect cognitive functions in patients with epilepsy, focusing on both neuropsychological and electrophysiological aspects.
- It involved a single-center study with 320 participants, including epilepsy patients and healthy controls, assessing cognitive function using the Montreal Cognitive Assessment (MoCA) and Event-Related Potentials (ERP) before and after ASM treatment.
- Findings revealed significant cognitive impairments in epilepsy patients compared to healthy controls, with specific ASMs like topiramate and carbamazepine showing detrimental effects on cognitive performance.
Article Synopsis
- Multiple sclerosis (MS) is a chronic neurological disease that affects various functions, including speech, motor ability, and cognition.
- The study analyzed speech disorders in 20 MS patients compared to 20 healthy individuals using specific speech analysis techniques and the PRAAT program.
- The K-nearest neighbor (K-NN) algorithm was identified as the most effective method (95% accuracy) for distinguishing between the speech features of MS patients and healthy controls.
Background: Although acute headache following COVID-19 vaccination is widely acknowledged, the long-term progression of these headaches remains poorly understood. Our objective was to identify various phenotypes of prolonged or worsened headaches associated with COVID-19 vaccination and document any changes in these phenotypes over an extended period. Additionally, we aimed to document the diverse headache presentations among patients with pre-existing primary headaches.
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- * The presentation of this condition can vary widely, including symptoms like cauda equina syndrome and acute inflammatory demyelinating polyradiculoneuropathy.
- * This case study is significant as it reports the first occurrence of leptomeningeal carcinomatosis manifesting with a unique variant of Guillain-Barré Syndrome and abnormal findings in cerebrospinal fluid called Froin's syndrome.
Article Synopsis
- * Data was gathered from a registry created by the European Academy of Neurology, involving 1523 COVID-19 patients across multiple countries, focusing on their demographics, medical history, and neurological issues.
- * Results showed that 79.6% of patients exhibited neurological symptoms, with cognitive dysfunction, stroke, and sleep disturbances being the most common; findings also indicated variations based on age and existing health conditions.
Objective: To investigate the possible subgroups of patients with Cluster Headache (CH) by using K-means cluster analysis.
Methods: A total of 209 individuals (mean (SD) age: 39.8 (11.
Erratum: The Effectiveness of Diet Restriction in Elderly with Migraine.
Noro Psikiyatr Ars
January 2022
[This corrects the article on p. 217 in vol. 58, PMID: 34526845.
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- The study investigates the relationship between headaches and idiopathic/genetic epilepsy (I/GE) in patients aged 6-40 years, focusing on headache prevalence and characteristics among these individuals.
- Out of 809 patients, 62.8% reported headaches, with 87.4% experiencing interictal headaches and 41.2% having migraines; the analysis identified distinct clusters based on headache and epilepsy features for both adults and children/adolescents.
- Two primary clusters emerged: one included patients with a family history of headaches and specific seizure types (like juvenile myoclonic epilepsy), while the other contained patients with different characteristics, including those with self-limited epilepsy and generalized tonic-clonic seizures. *
Introduction: Coronavirus disease (COVID-19) is an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The disease was declared a pandemic on March 11th, 2020, by the World Health Organization (WHO). There has been a substantial increase in the epileptic seizures and status epilepticus reported in the pandemic period.
View Article and Find Full Text PDFGreater occipital nerve block efficacy in COVID‑19 associated headache: a preliminary study.
Acta Neurobiol Exp (Wars)
January 2022
COVID‑19 is an infection caused by the new coronavirus SARS‑CoV‑2. Headache is one of the most common neurological findings. In the treatment of various chronic headaches, the greater occipital nerve (GON) block is often used as a safe and effective method.
View Article and Find Full Text PDFBackground And Aim: Pathogenesis of COVID-19 -related headache is unknown, though the induction of the trigeminal neurons through inflammation is proposed. We aimed to investigate key systemic circulating inflammatory molecules and their clinical relations in COVID-19 patients with headache.
Methods: This cross-sectional study enrolled 88 COVID-19 patients, hospitalized on a regular ward during the second wave of the pandemic.
Cognitive Profile of Patients with Thalamic Hemorrhage according to Lesion Localization.
Dement Geriatr Cogn Dis Extra
May 2021
Article Synopsis
- The thalamus serves as a key relay station for sensory and motor functions in the brain, and lesions in this area can lead to cognitive decline, with effects varying based on lesion location.
- In a study involving 28 patients with thalamic hemorrhage, detailed neurophysiological tests showed that these patients performed significantly worse on cognitive tests compared to a control group.
- Findings indicated that the anteromedial lesions were linked to the poorest cognitive scores, while the lateral part was associated with language issues and the posterior part with memory problems, highlighting the overall impact of thalamic hemorrhages on cognitive functioning.
Background And Objective: Clinical studies on COVID-19 headache are limited. This prospective study aimed to define headache characteristics, associated clinical and laboratory factors, and treatment response in COVID-19.
Methods: Cross-sectional study enrolled 287 patients diagnosed with COVID-19 and hospitalized on a regular ward during the pandemic.
Article Synopsis
- The study aims to examine normal MRS features of the trigeminal nerve and compare metabolite concentrations in trigeminal neuralgia patients' affected and unaffected nerves.
- A total of 33 patients underwent MR studies, measuring various metabolites like NAA, Cr, and Cho, with significant differences found in metabolite concentrations on the affected side.
- Results indicated higher Cr concentrations in all parts of the affected nerves, with notable differences in NAA and myoinositol concentrations as well; vascular conflicts were present in a majority of patients, often correlating with neuralgia symptoms.
Background/aim: Coronavirus 2019 disease (Covid-19) was first seen in December 2019 and afterwards it became pandemic. Several systemic involvements have been reported in Covid-19 patients. In this study, it was aimed to investigate the cerebrovascular hemodynamics in patients with Covid-19.
View Article and Find Full Text PDFIntroduction: Arrhythmias are one of the most common causes of mortality in patients with acute ischemic stroke (AIS). This study aimed to investigate the relationships of arrhythmia susceptibility markers (QT, QTc, Tpe, Tpe-D, Tpe/QT, and Tpe/QTc) with the localization and volume of the ischemic area, the National Institutes of Health Stroke Scale (NIHSS) scores, and troponin levels in AIS.
Methods: Patients diagnosed with AIS in the emergency department in the period from 01 November 2016 to 31 March 2019 were retrospectively reviewed.
Background: COVID-19 is a virus pandemic. According to the first obtained data, COVID-19 has defined with findings such as cough, fever, diarrhea, and fatigue although neurological symptoms of patients with COVID-19 have not been investigated in detail. This study aims to investigate the neurological findings via obtained face-to-face anamnesis and detailed neurological examination in patients with COVID-19.
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- The study investigates the impact of dietary changes by eliminating certain triggering foods on migraine attacks in elderly patients (65+ years old) diagnosed with migraine without aura.
- Conducted on 31 participants, the research measured various factors like attack frequency, duration, and pain intensity before and after the dietary intervention.
- Results showed significant reductions in the frequency, duration, and severity of migraine attacks, indicating that dietary modifications can effectively reduce medication usage in older migraine sufferers.
Aim: To find a more practical and effective formula than simple ABC/2 (sABC/2) to calculate the hematoma volume in patients with subdural and parenchymal haemorrhage.
Material And Methods: We reviewed the records of 157 patients who underwent brain computed tomography examinations for stroke from January to October 2017. Our method, sABC/2 formula, and the planimetric method (the gold standard) were used for measuring the volumes of hematoma.