Publications by authors named "Omer Kamer"

Bile acids (BAs) undergo extensive microbial metabolism in the gut and exert hormone-like functions on physiological processes underlying metabolic risk. However, the extent to which gut BA profiles predict cardiometabolic risk and explain individual responses to dietary interventions in humans is still unclear. In the DIRECT-PLUS Trial, we conducted a multi-omics analysis of 284 participants randomized into three groups: healthy dietary guidelines and two Mediterranean diet (MedDiet) groups.

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Aim: To explore the effect of Mankai, a cultivated aquatic duckweed green plant, on postprandial glucose (PG) excursions in type 2 diabetes (T2D).

Methods: In a 4-week, randomized crossover-controlled trial, we enrolled 45 adults with T2D (HbA1c range: 6.5%-8.

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Article Synopsis
  • Autologous fecal microbiota transplantation (aFMT) combined with a high-polyphenol Mediterranean diet helped prevent weight regain and insulin rebound after participants lost weight over six months.
  • The study analyzed the gut microbiome of 82 obese participants to see how changes in core (abundant) and non-core (low-abundance) gut bacteria during weight loss influenced their ability to maintain weight after aFMT treatment.
  • Results showed that participants with minimal changes in core bacteria and significant changes in non-core bacteria were more successful in avoiding weight regain, highlighting the importance of non-core taxa in weight maintenance post-aFMT.
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