Publications by authors named "Omer Aviv"
Article Synopsis
- Surface ligands on semiconductor nanocrystals significantly influence their stability and properties, thereby enabling their use in various applications.
- The study used isothermal titration calorimetry to analyze how different structural features of ligand chains, particularly in branched versus linear alkylthiols, affect the thermodynamics of ligand exchange on CdSe nanocrystals.
- Results indicate that branched ligands exhibit lower energy release and entropy loss during exchange compared to linear ones, leading to a deeper understanding of ligand design for optimizing nanocrystal applications.
Background: T and B cell receptor (TCR, BCR) repertoires constitute the foundation of adaptive immunity. Adaptive immune receptor repertoire sequencing (AIRR-seq) is a common approach to study immune system dynamics. Understanding the genetic factors influencing the composition and dynamics of these repertoires is of major scientific and clinical importance.
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- Surface ligands on semiconductor nanocrystals (NCs) significantly influence their properties and applications.
- Isothermal titration calorimetry directly measures key thermodynamic characteristics of ligand exchange from oleate-capped CdSe NCs to alkylthiols, revealing the impact of ligand chain length on reaction behavior.
- Findings show that longer ligands increase reaction heat release and lower entropy, while smaller NCs exhibit greater spontaneity due to higher surface reactivity, informing future NC surface ligand design.
VDJbase: an adaptive immune receptor genotype and haplotype database.
Nucleic Acids Res
January 2020
Article Synopsis
- - VDJbase is a free database that provides detailed gene sequence data from studies of immune receptor repertoires, allowing researchers to investigate genetic differences in immunoglobulin and T cell receptor genes.
- - The platform offers tools for users to visualize and analyze genotype and haplotype data, helping identify genetic predispositions to diseases by highlighting prevalent alleles in different populations.
- - Users can access VDJbase without a login at https://www.vdjbase.org/, and all data and code are available for download under creative commons licenses.