Publications by authors named "Omeed Maghzian"
Article Synopsis
- The initially published paper did not declare any competing interests.
- It was later revealed that B.M.N. is on the Scientific Advisory Board of Deep Genomics.
- The error has now been corrected in both the HTML and PDF versions of the article.
Article Synopsis
- An amendment to the original paper has been published.
- The amendment can be accessed through a link provided at the top of the paper.
- This update may contain important revisions or additional information relevant to the initial findings.
Article Synopsis
- * The identified SNPs are linked to genes that influence brain development and communication between neurons, suggesting a biological basis for educational achievement.
- * Additionally, we analyzed the X chromosome and found 10 more significant SNPs, with our models explaining 11-13% of the variance in educational attainment, enhancing the potential of polygenic scores in research.
We introduce multi-trait analysis of GWAS (MTAG), a method for joint analysis of summary statistics from genome-wide association studies (GWAS) of different traits, possibly from overlapping samples. We apply MTAG to summary statistics for depressive symptoms (N = 354,862), neuroticism (N = 168,105), and subjective well-being (N = 388,538). As compared to the 32, 9, and 13 genome-wide significant loci identified in the single-trait GWAS (most of which are themselves novel), MTAG increases the number of associated loci to 64, 37, and 49, respectively.
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