Publications by authors named "Omar Oliva"
Objectives: This study aimed to detail the technical management of Medina 0.0.1 lesions, assess their outcomes, and identify predictors of Major Adverse Cardiovascular Events (MACE).
View Article and Find Full Text PDFOver the past few years, transcatheter aortic valve implantation (TAVI) imposed itself as the first-choice therapy for symptomatic aortic stenosis (AS) in elderly patients at surgical risk. There have been continuous technological advancements in the latest iterations of TAVI devices and implantation techniques, which have bolstered their adoption. Moreover, the favorable outcomes coming out from clinical trials represent an indisputable point of strength for TAVI.
View Article and Find Full Text PDFTransjugular Transcatheter Tricuspid Valve Replacement: Early Compassionate Use Outcomes.
JACC Cardiovasc Interv
August 2024
Article Synopsis
- A study assessed the procedural and early outcomes of transjugular transcatheter tricuspid valve replacement (TTVR) for patients with symptomatic tricuspid regurgitation using the LuX-Valve Plus system across 15 centers from January 2022 to February 2024.
- Among 76 patients with a median age of 78, the procedure significantly reduced tricuspid regurgitation, with 95% of patients showing improvement at one month.
- While there were some adverse events including 4 in-hospital deaths and some bleeding, overall survival at one month was high at 94.4%, and patients reported better functional status.
Article Synopsis
- This study explores how the curvature and angulation of the aortic landing zone (LZ) can influence the depth of transcatheter aortic valve implantation (TAVI) using different types of devices: balloon-expanding (BE) and self-expanding (SE) valves.* -
- Researchers found that SE devices exhibited greater LZ curvature and angulation characteristics compared to BE devices, affecting how deep the valves were implanted in patients.* -
- The study concluded that greater LZ curvature (specifically at angles above 17.8°) was a reliable predictor of deeper implantation for SE devices, suggesting that device selection and anatomical factors need to be carefully considered during TAVI procedures.*
Three-year clinical outcomes after transcatheter aortic valve implantation in patients with bicuspid aortic disease: Comparison between self-expanding and balloon-expandable valves.
Catheter Cardiovasc Interv
May 2024
Article Synopsis
- Bicuspid aortic valve (BAV) stenosis poses challenges for transcatheter aortic valve implantation (TAVI), with positive short-term results but limited long-term data available.
- A study analyzed 150 patients who underwent TAVI comparing self-expanding valves (SEV) and balloon-expandable valves (BEV), looking at outcomes like mortality, stroke, and the need for valve reintervention over three years.
- Results showed no significant differences in primary or secondary outcomes between SEV and BEV groups, indicating similar long-term clinical effectiveness for both valve types in BAV patients.
We describe a rare and extremely challenging case of transcatheter pulmonary valve implantation in repaired tetralogy of Fallot and anomalous origin of the left main coronary artery from the right coronary sinus. Procedural planning based on advanced multimodality imaging and 3-dimensional technology proved to be the key to procedural success.
View Article and Find Full Text PDFRight disc thrombosis of the new Gore Cardioform ASD Occluder.
Catheter Cardiovasc Interv
April 2024
Background: The GCA is a well performing device in terms of efficacy despite complex anatomies (aortic rim <5 mm and ASD diameter >17 mm) with a good safety profile.
Aims: To evaluate atrial septal defect (ASD) features impacting on right disc device thrombosis in patients who underwent Gore Cardioform ASD Occluder (GCA) implantation.
Methods: A total of 44 consecutive patients undergoing percutaneous ASD with GCA device from January 2020 to September 2022 at our tertiary care Center were evaluated.
Bicuspid aortic valve (BAV) is the most common congenital heart disease, with a prevalence of 1-2% and occurring in >20% of octogenarians referred for aortic valve replacement. However, BAV patients have been systematically excluded from pivotal randomized trials. Since TAVI indications are moving toward low-risk patients, an increase in the number of BAV patients who undergo TAVI is expected.
View Article and Find Full Text PDFAims: In acute heart failure (AHF), kidney congestion is basic to treatment and prognosis. Its aetiology is manifold and quite unexplored in details mainly regarding the right heart to pulmonary circulation (Pc) coupling. We investigated the right heart to kidney interrelationship by Doppler renal flow pattern, right atrial dynamics, and right ventricular (RV) function to Pc coupling in AHF.
View Article and Find Full Text PDFAccurate planning of transcatheter aortic valve implantation (TAVI) is important to minimize complications, and it requires anatomic evaluation of the aortic root (AR), commonly performed through 3D computed tomography (CT) image analysis. Currently, there is no standard automated solution for this process. Two convolutional neural networks with 3D U-Net architectures (model 1 and model 2) were trained on 310 CT scans for AR analysis.
View Article and Find Full Text PDFBackground: The impact of nodular calcifications in left ventricular outlow tract (LVOT) and aortic annulus on the procedural outcome of transcatheter aortic valve implantation (TAVI) with new-generation devices is yet to be elucidated. Similarly, computational simulations may provide a novel insight into the biomechanical features of TAVI devices and their interaction with nodular calcifications.
Methods: This retrospective single-center study included 232 patients submitted to TAVI with Evolut-R (53.
Objectives: To evaluate the prognostic impact of baseline tricuspid annular plane systolic excursion/pulmonary artery systolic pressure (TAPSE/PASP) ratio, as an expression of the right ventricle-pulmonary artery (RV-PA) coupling, in patients with mitral regurgitation (MR) treated with the MitraClip.
Background: Impaired RV to PA coupling is considered a marker of RV dysfunction.
Methods: From February 2016 to February 2020, a total of 165 patients were evaluated and stratified in two groups according to a prespecified value of TAPSE/PASP ratio ≤ 0.
Redo transcatheter aortic valve replacement (TAVR) may pose the risk of coronary flow obstruction. We report 2 cases of severe TAVR regurgitation due to different physiopathological mechanisms in which TAVR-in-TAVR could be at high risk for sinus sequestration. Both cases were successfully treated by in-series implantation of a second transcatheter heart valve, thus avoiding sinus sequestration.
View Article and Find Full Text PDFEpicardial fat inflammation response to COVID-19 therapies.
Obesity (Silver Spring)
September 2021
Objective: Adipose tissue plays a role in the novel coronavirus disease 2019 (COVID-19). Epicardial adipose tissue (EAT), a unique visceral fat, presents with a high degree of inflammation in severe COVID-19. Whether and how adipose tissue may respond to the COVID-19 therapies is unknown.
View Article and Find Full Text PDFPurpose: To compare in-hospital outcome of Evolut-R 34 mm vs. smaller Evolut-R devices and to identify predictors of paravalvular leak (PVL) and deep implantation specific for Evolut-R 34 mm.
Methods: This single-center retrospective study included 359 consecutive patients undergoing transcatheter aortic valve replacement (TAVR) with Evolut-R 34 mm (N = 84,23.