Low vs. conventional intra-abdominal pressure in laparoscopic colorectal surgery: a prospective cohort study.

Purpose: Low intraabdominal pressure (IAP) during laparoscopy is associated with improved post-operative outcomes across a variety of surgical specialties. A prospective cohort study was undertaken to assess post-operative outcomes in patients undergoing laparoscopic colorectal surgery (LCRS) with low (8mmHg) versus conventional (15mmHg) IAP.

Methods: A prospective real-world observational study of patients undergoing LCRS in a single-centre, between June 2020 and June 2023 was performed.

Meta-analysis of routine abdominal drainage versus no drainage following distal pancreatectomy: Does the best available evidence overcome "HPB surgeon's paranoia"?

Aims: To evaluate comparative outcomes of routine abdominal drainage versus no drainage after distal pancreatectomy (DP).

Methods: A systematic search of MEDLINE, CENTRAL and Web of Science and bibliographic reference lists were conducted (last search: 20th April 2024). All comparative studies reporting outcomes of DP with routine abdominal drainage and no drainage were included and their risk of bias were assessed.

Optimized neural network-based model to predict the shear strength of trapezoidal-corrugated steel webs.

Beam-like members use corrugated webs to increase their shear strength, stability, and efficiency. The corrugation positively affects the members' structural characteristics, especially those governed by the web parameters, such as the shear strength, while reducing the total weight. Existing code and analytical models for predicting the shear strength of trapezoidal corrugated steel webs (TCSWs) are summarized.

Self-limiting material growth triggered and tunable by force through piezocharge-induced mineralization.

Controlling the growth of material is crucial in material processing for desired properties. Current approaches often involve sophisticated equipment for controlling precursors and monitoring material formation. Here we report a self-limiting material growth mechanism controlled by the experienced mechanical loading without the need for precise control over precursors or monitoring material growth.

Do Hypoalbuminaemia Increase the Risk of Surgical Site Infection in Neck of Femur Fracture Patients: A Systematic Review and Meta-Analysis.

Serum albumin plays an important role in physiological and inflammatory haemostasis, and low serum levels are linked with an increased incidence of surgical site infections (SSI). Although this has been demonstrated in the spine and elective arthroplasty settings, there is a paucity of evidence with regard to the effect of low serum albumin on rates of SSI following surgery for adult patients suffering from traumatic and acute hip fractures. A systematic review was conducted using the PRISMA guidelines.

Level 1a Evidence Comparing Use of Antibiotics Versus No Antibiotics in Management of Acute Left-Sided Uncomplicated Diverticulitis.

Background: Acute uncomplicated diverticulitis (AUD) is a common cause of acute abdominal pain. Recent guidelines advise selective use of antibiotics in AUD patients. This meta-analysis aimed to compare the effectiveness of no antibiotics vs antibiotics in AUD patients.

Evaluation of National Anaesthetics Teaching in Undergraduate Medicine (ENATUM).

Background: During a global pandemic where anaesthetists play a pertinent role in treating coronavirus 2019 (COVID-19), it is crucial to inspire medical students to consider a career in anaesthetics and perioperative care. Where anaesthetic skills are vital for all surgical foundation doctors, regardless of whether they have a rotation in anaesthetics, this study seeks to establish the current level of exposure to anaesthetics in the UK medical schools' curriculum and evaluate if the current anaesthetic undergraduate curriculum is sufficient to prepare students to pass their exams and perform the duties expected of them as future junior doctors.

Methods: A 35-item structured questionnaire, registered at University College London Hospital Research & Development (R&D), was distributed amongst foundation doctors who had graduated from UK universities within the previous 3 years between August and October 2020.

Toothpick perforates small bowel-mimicking diverticulitis.

Bowel perforation is an emergency condition that requires critical thinking and readily intervention; nevertheless, on occasions, its presentation can be challenging to diagnose. Several etiologies could cause bowel perforation, including obstruction, mass, inflammation, ischemia, etc. On rare occasions, a foreign body could be the cause of perforation, which mandates a detailed history and focused review of the images when the patient's condition allows.

Hepatojugular 'reflex' or 'reflux'? A tale of two vowels.

Summary: Hepatojugular reflux is an important, prognostic clinical sign in the field of medicine. The majority of medical students or clinicians may attempt to elicit this sign during abdominal or cardiovascular examinations. However, some individuals may incorrectly call it the hepatojugular 'reflex' rather than a 'reflux'.

Blood Group and Response to Bariatric Surgery in Morbidly Obese Patients: A Retrospective Study in Saudi Arabia.

Objectives: To explore the relationship between the blood group of patients and their response to bariatric surgery and to identify predictors of better outcomes.

Methods: This was a retrospective cross-sectional analysis of patients who underwent laparoscopic sleeve gastrectomy for morbid obesity between 2014 and 2020 at King Saud University Medical City in Riyadh, Saudi Arabia.

Results: This study included 1434 individuals.

Foreseeing metal failure from its inception.

The life span of metals can be inferred from early microscopic deformation events.

Parental perception of medications safe storage in the State of Qatar.

Purpose: The purpose of this study is to identify parental perception of household medication storage.

Methods: A prospective cross-sectional study utilizing a questionnaire was carried out at Hamad Medical Corporation, the solely tertiary pediatric hospital in the State of Qatar at the time of the study. Qatar is a young developing country with limited data on the awareness of medication storage among adults with children at home and on the safety practices regarding medication storage.

Medication take-back programs in Qatar: Parental perceptions.

Purpose: To identify parental perception of a take-back program for medications.

Materials And Methods: A cross-sectional study using a questionnaire was conducted at Hamad Medical Corporation, the only tertiary pediatric hospital in the State of Qatar at the time of the study. Qatar is a rapidly developing country with limited national data on the awareness of medication misuse among adults living with children at home and on the safety practices regarding medication disposal.

Good reactions for low-power shape-memory microactuators.

Microscale programmable shape-memory actuators based on reversible electrochemical reactions can provide exciting opportunities for microrobotics.

The Nomenclature of Electroconvulsive Therapy.

Electroconvulsive therapy (ECT) is an established but stigmatized psychiatric treatment. The term ECT reflects the treatment's modality and action. Several authors proposed different names for ECT to deal with stigma; however, available literature that promoted different names did not address the risk/benefit ratio or offer evidence-based approach to the efficacy of this approach.

Novel mineralized electrospun chitosan/PVA/TiO nanofibrous composites for potential biomedical applications: computational and experimental insights.

Electrospun nanofibrous materials serve as potential solutions for several biomedical applications as they possess the ability of mimicking the extracellular matrix (ECM) of tissues. Herein, we report on the fabrication of novel nanostructured composite materials for potential use in biomedical applications that require a suitable environment for cellular viability. Anodized TiO nanotubes (TiO NTs) in powder form, with different concentrations, were incorporated as a filler material into a blend of chitosan (Cs) and polyvinyl alcohol (PVA) to synthesize composite polymeric electrospun nanofibrous materials.

Robust photoactive nanoadsorbents with antibacterial activity for the removal of dyes.

ZnO nanostructures (NS)/guar gum (GG) nanocomposites have been successfully synthesized and tested as sorbents for photodegradation, adsorption and antimicrobial activity for dye removal. The addition of ZnO improves the thermal stability of GG based on the ratio of the oxygen in the OH form and the total oxygen in the samples as indicated via XPS and FTIR analyses. Among all tested composites, the ZnO NPs/GG nanocomposite showed the highest photocatalytic activity and hence used in extended adsorption and degradation studies against the anionic dye reactive red (RR195) and the cationic dye Rhodamine B (RhB).

Effect of Dexmedetomidine Versus Nalbuphine as an Adjuvant on Paravertebral Block to Manage Postoperative Pain After Mastectomies.

Background And Objective: Breast cancer is the commonest cancer in women worldwide. Many patients are frequently admitted to the operating theaters for mastectomies. Thoracic paravertebral block (PVB) is increasingly used as an effective means for post-operative pain relief.

Cellular fibronectin expression in chronic hepatitis C virus patients.

Background: Hepatitis C virus (HCV) is associated with fibrosis, cirrhosis, hepatocellular carcinoma (HCC), and end-stage liver disease. In the normal liver, fibronectin plays crucial roles in various cellular functions, including cell adhesion, migration, proliferation, and differentiation. Increased expression of fibronectin is associated with areas of physiological or pathological tissue remodeling, including wound healing and tissue repair.

Effect of anodal versus cathodal transcranial direct current stimulation on stroke rehabilitation: a pilot randomized controlled trial.

Objective: We compared the long-term effect of anodal versus cathodal transcranial direct current stimulation (tDCS) on motor recovery in patients after subacute stroke.

Methods: Forty patients with ischemic stroke undergoing rehabilitation were randomly assigned to 1 of 3 groups: Anodal, Cathodal (over-affected and unaffected hemisphere, respectively), and Sham. Each group received tDCS at an intensity of 2 mA for 25 minutes daily for 6 consecutive days over of the motor cortex hand area.