Endothelial progenitor cell-derived small extracellular vesicles for myocardial angiogenesis and revascularization.

Background: Endothelial progenitor cells (EPCs) have been well-studied for their differentiation potential and paracrine activity in vitro and in experimental animal studies. EPCs are the precursors of endothelial cells (ECs) and a rich source of pro-angiogenic factors, and hence, possess enormous potential to treat ischemic heart through myocardial angiogenesis. Their proven safety and efficacy observed during the pre-clinical and clinical studies have portrayed them as a near ideal cell type for cell-based therapy of ischemic heart disease.

Life cycle assessment of biocemented sands using enzyme induced carbonate precipitation (EICP) for soil stabilization applications.

Integrating sustainability goals into the selection of suitable soil stabilization techniques is a global trend. Several bio-inspired and bio-mediated soil stabilization techniques have been recently investigated as sustainable alternatives for traditional techniques known for their high carbon footprint. Enzyme Induced Carbonate Precipitation (EICP) is an emerging bio-inspired soil stabilization technology that is based on the hydrolysis of urea to precipitate carbonates that cement sand particles.

Macro and micro geo-spatial environment consideration for landfill site selection in Sharjah, United Arab Emirates.

Waste management involves various procedures and resources for proper handling of waste materials in compliance with health codes and environmental regulations. Landfills are one of the oldest, most convenient, and cheapest methods to deposit waste. However, landfill utilization involves social, environmental, geotechnical, cost, and restrictive regulation considerations.

Prophylactic effects of ellagic acid and rosmarinic acid on doxorubicin-induced neurotoxicity in rats.

Doxorubicin (DOX) is a chemotherapeutic agent widely used in human malignancies. Its long-term use cause neurobiological side effects. The aim of the present study was to investigate the prophylactic effect exerted by daily administration of ellagic acid (EA) and rosmarinic acid (RA) on DOX-induced neurotoxicity in rats.

Ellagic acid and rosmarinic acid attenuate doxorubicin-induced testicular injury in rats.

The anticancer drug doxorubicin causes testicular toxicity as an undesirable effect. The present study was undertaken to investigate the possible protection of ellagic acid and rosmarinic acid during doxorubicin administration. For this purpose eight groups of male Sprague-Dawley rats were used (n = 10), one group received vehicle served as control, and other groups received 5 mg/kg doxorubicin twice a week for 2 weeks for a cumulative dose of 20 mg/kg, ellagic acid (10 mg/kg/day, 14 consecutive days p.

In vivo and in vitro evaluation of the effects of domperidone on the gastrointestinal tract of healthy horses.

Objective: To determine the effects of domperidone on in vivo and in vitro measures of gastrointestinal tract motility and contractility in healthy horses.

Sample: 18 adult horses and tissue samples from an additional 26 adult horses.

Procedures: Domperidone or placebo paste was administered to healthy horses in a 2-period crossover study.

Pharmacokinetics, pharmacodynamics, and safety of zoledronic acid in horses.

Objective: To determine the pharmacokinetics, pharmacodynamics, and safety of zoledronic acid in horses.

Animals: 8 healthy horses.

Procedures: A single dose of zoledronic acid (0.

Use of zoledronate for treatment of a bone fragility disorder in horses.

Objective: To assess clinical outcomes and scintigraphic findings in horses with a bone fragility disorder (BFD) treated with zoledronate (a nitrogen-containing bisphosphonate).

Design: Prospective uncontrolled clinical trial.

Animals: 10 horses with evidence of a BFD.

Abdominal computed radiography for the diagnosis of enterolithiasis in horses: 142 cases (2003?2007).

Objective: To evaluate the sensitivity and specificity of abdominal computed radiography (CR) for the diagnosis of enterolithiasis in horses and to examine how these parameters are affected by the number and anatomic location of enteroliths and by gas distension of the gastrointestinal tract.

Design: Retrospective case series.

Animals: Horses ? 1 year old that underwent abdominal CR and subsequent exploratory laparotomy or postmortem examination.

Evaluation of the effect of ranitidine on gastroduodenal contractile activity and gastric emptying in horses.

Objective: To determine the effect of ranitidine on gastric emptying in horses.

Animals: 11 adult horses.

Procedures: In vitro, isolated muscle strips from the pyloric antrum and duodenum of 5 horses were suspended in baths and attached to isometric force transducers.

Pull-through technique for palmar digital neurectomy: forty-one horses (1998-2004).

Objectives: To report outcome of horses treated for navicular syndrome using a pull-through (PT) technique for palmar digital neurectomy (PDN).

Design: Retrospective study.

Animals: Horses (n=41) with navicular syndrome (NS).