Differentiating mycosis fungoides lesions from their mimickers clinically and histologically: A single tertiary center retrospective analysis in Saudi Arabia.

Objectives: To identify the clinical and histological features of MF that can assist in distinguishing MF from MF-mimicking cases. Although mycosis fungoides (MF) is the most common subtype of cutaneous T-cell lymphoma, clinicopathological correlations are required to establish an accurate diagnosis, which are currently lacking.

Methods: This retrospective observational study evaluated the clinical presentations, characteristics, and histological features of 56 patients with suspected MF who presented to our clinic between January 2018 and August 2022.

Infantile Bullous Pemphigoid: A Case Report.

Background: Infantile bullous pemphigoid (IBP) is an exceptionally rare acquired autoimmune subepidermal bullous disorder characterized by vesicles, bullae, and additional manifestations, such as urticarial and infiltrated papules, plaques, or eczematous lesions. These skin lesions can lead to eroded and crusted regions after healing, and in some cases, rapid blister rupturing causes extensively eroded areas. Reporting these rare cases is crucial to improving our understanding, diagnosis, and treatment of IBP.

Filaggrin gene variants among Saudi patients with ichthyosis vulgaris.

Ichthyoses are a heterogeneous group of cornification disorders. The most common form of ichthyoses is ichthyosis vulgaris (IV) ([OMIM] #146,700), which can be inherited as autosomal semi-dominant mutation in the filaggrin gene (FLG). We present the findings of a study involving 35 Saudi patients with a clinical diagnosis of ichthyosis vulgaris.

Unknown mutations and genotype/phenotype correlations of autosomal recessive congenital ichthyosis in patients from Saudi Arabia and Pakistan.

Background: Autosomal recessive congenital ichthyosis (ARCI) is a genetically and phenotypically heterogeneous skin disease, associated with defects in the skin permeability barrier. Several but not all genes with underlying mutations have been identified, but a clear correlation between genetic causes and clinical picture has not been described to date.

Methods: Our study included 19 families from Saudi Arabia, Yemen, and Pakistan.

Acne neonatorum in the eastern Saudi Arabia.

Background: Acne neonatorum (AN) is characterized by a facial eruption of inflammatory and noninflammatory acne lesions in a neonate. Hyperactivity of sebaceous glands, stimulated by neonatal androgens, is implicated in its pathogenesis.

Aim: To elucidate the clinical profile of AN in eastern Saudi Arabia.

Herpes zoster in eastern Saudi Arabia: clinical presentation and management.

Background: Herpes zoster (HZ), caused by varicella zoster virus (VZV), initially produces chicken-pox, then the virus lies dormant in the dorsal root ganglia. The virus can reactivate after many years and results in HZ along ganglion's distribution. Old age, trauma, stress, diabetes mellitus, and immune suppression are important risk factors for the reactivation.

Pattern of skin diseases in Eastern Saudi Arabia.

Objectives: To describe the pattern of skin disease in the Eastern Province and compare it with similar studies carried out in other regions of Saudi Arabia.

Methods: All new dermatology cases reporting at King Fahd Hospital of the University in Al-Khobar, Saudi Arabia, seen between August 2002 to July 2003 were reviewed.

Results: One thousand and seventy-six new patients within the period of the study were seen.

Antidermatophyte activity of ether extract of Nigella sativa and its active principle, thymoquinone.

The antifungal activity of ether extract of Nigella sativa seed and its active principle thymoquinone was tested against eight species of dermatophytes: four species of Trichophyton rubrum and one each of Trichophyton interdigitale, Trichophyton mentagrophytes, Epidermophyton floccosum and Microsporum canis. Agar diffusion method with serial dilutions of ether extract of Nigella sativa, thymoquinone and griseofulvin was employed. The incubation was carried out at 30 degrees C for 14 days.

Association of atopic dermatitis with primary hereditary ichthyoses.

Objective: The aim of this study is to find out the association of atopic dermatitis and other atopic features with primary hereditary ichthyosis (PHI) among Saudi patients in King Fahd Hospital of the University, Al-Khobar, Kingdom of Saudi Arabia.

Methods: From the out-patient Department of Dermatology logbooks, all Saudi patients with clinically and histopathologically confirmed PHI seen between January 1990 and December 1995 were included in this study. Clinical findings regarding the atopic manifestations of PHI were extracted into data collection forms and computer-analyzed, using Statistical Package for Social Sciences.

Demographic features and seasonal variations in patients with acne vulgaris in Saudi Arabia: a hospital-based study.

Aim: To review the demographic features and seasonal variations of acne vulgaris in patients diagnosed at the Dermatology Outpatient Clinic, King Fahad Hospital of the University (KFHU), Al-Khobar, Saudi Arabia.

Methods: Two hundred and twenty cases (142 females, 78 males; mean age, 14.8 and 16.

Clinical pattern of acne vulgaris and its associated conditions in the eastern province of kingdom of saudi arabia: a hospital-based clinical study.

Objective: This study aims to review the clinical pattern of acne vulgaris cases referred to one hospital in the Eastern Province.

Methods: Two hundred cases diagnosed in the Dermatology Department at King Fahad Hospital of the University (KFHU), Al-Khobar, Saudi Arabia were studied

Results: Inflammatory acne was the predominant type observed in both males and females (76% and, 79%, respectively). Seborrhea (greasy skin) was the most frequently associated condition 22 (11%) followed by dandruff 8 (4%).