Publications by authors named "Omar Gonzalez- Santiago"

Objective: To describe the recent trends in Parkinson's disease mortality in Mexico during 2000-2020.

Method: The adjusted mortality rate per 100,000 inhabitants was calculated using the direct method and the world standard population. Trend analysis was performed with the Joinpoint software.

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Introduction: Mortality is affected by several factors, including the place of residence. Several studies have found a gap in mortality between urban and rural residents. This study aimed to describe adjusted mortality rates in urban and rural areas of Mexico.

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Alcohol is the main cause of liver cirrhosis. The objective of this study was to analyze the mortality rates of alcohol-related cirrhosis in Mexico from 2000 to 2017. Mortality data from alcohol-related cirrhosis were obtained from the National Institute of Statistics and Geography.

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Article Synopsis
  • The study focused on synthesizing silver nanoparticles (NP) using two different methods: an aqueous leaf extract and citrate ions as a stabilizer, then evaluated their anticancer properties and cytotoxicity in a lab setting.
  • The silver NPs made with the leaf extract were spherical and ranged in size from 15 to 45 nm, showing a reduction in cell viability across various cell types, with a specific inhibitory concentration (IC) identified in Chang liver cells.
  • Both types of nanoparticles were found to lower reactive oxygen species production and caspase-3 activity, indicating their potential for anticancer use; however, further research is necessary to understand their exact cell death mechanisms, which likely differ from typical apoptosis.
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There is extensive evidence to believe that the endocannabinoid system plays an important role in energy homeostasis through a variety of mechanisms. This study aimed to analyze the association between polymorphism rs12720071 of the cannabinoid type 1 receptor (CNR1) gene with dyslipidemia and overweight in young, healthy Mexicans. The association was analyzed with a logistic regression model and expressed as odds ratio (OR).

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Aim: Recent studies show an association between the endocannabinoid system and pain. In this study, we analyzed the association between two CNR1 gene polymorphisms and pain perception in a northeast Mexican population.

Methods: Genotypic and allelic frequencies were obtained for both polymorphisms.

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Antecedentes: Una de las principales complicaciones de la diabetes mellitus es la amputación de alguna extremidad. En todo el mundo, la prevalencia de amputaciones asociadas a la diabetes es muy variada y tiene un impacto considerable en la calidad de vida del paciente.

Objetivo: Analizar la frecuencia de las amputaciones en el Hospital Universitario Dr.

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The five-year survival rate remains low for pancreatic cancer (PC). The objective of this study was to describe PC mortality rates in Mexico and its seven socioeconomic regions. The data for the deaths were obtained from the National Institute of Statistics and Geography databases.

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Introduction: Poisoning remains a major worldwide public health problem. Mortality varies by country, region and ethnicity. The objective of this study is to analyze recent trends in poisoning mortality in the Mexican population.

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Background. Medications are not exempt from adverse drug reactions (ADR) and how the physician perceives the risk of prescription drugs could influence their availability to report ADR and their prescription behavior. Methods.

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Presently the search for new drugs from natural resources is of growing interest to the pharmaceutical industry. Natural products have been the source of new drugs since ancient times. Plants are a good source of secondary metabolites which have been found to have beneficial properties.

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Background: The mechanisms responsible for the development of acute pancreatitis (AP) and its complications are not fully understood.

Aim: To assess the role of clinical and host molecular factors for the development and outcome of persistent systemic inflammatory response syndrome (SIRS) in patients with AP.

Methods: We included 191 patients with AP in the study.

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Objective: To analyze the place of death from cancer in México from 1999 to 2009 and find the associated factors.

Methods: We collected data on mortality by cancer from the national database including age, gender, area of residence, level of education, place of death, and type of cancer.

Results: The proportion of deaths at home and hospital was 55.

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Background: The incidence of coagulase-negative staphylococci reported as causative agents of nosocomial infections has risen in the last decade. The aim of this study was to characterize biofilm formation, antibiotic resistance, SCCmec type, and genetic relatedness in clinical isolates of Staphylococcus cohnii, Staphylococcus hominis, and Staphylococcus sciuri recovered from humans.

Methods: Clinically relevant isolates of S.

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The Monterrey Metropolitan Area (MMA) is the third largest city in Mexico. Few studies have been carried out regarding its air pollution. The aim of this study was to analyze the temporal behavior of PM10 (particulate matter < or =10 microm in aerodynamic diameter).

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Tuberculosis (TB) kills about 3 million people per year worldwide. Furthermore, TB is an infectious disease associated with HIV patients, and there is a rise in multidrug-resistant TB (MDR-TB) cases around the world. There is a need for new anti-TB agents.

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