Synthetic Cannabinoids are Genotoxic in Cultured Human Lymphocytes.

Background: Synthetic cannabinoids are one of the most identified abused drugs nowadays. Their popularity is due to their psychoactive effects, which resemble delta 9 tetrahydrocannabinol. This study investigates the genotoxic potential of three synthetic cannabinoids of indazole-passed drugs, AB-Fubinaca, AMBFubinaca, and EMB-Fubinaca (at a final concentration of 200 nM).

Enalapril protect human lymphocytes from genotoxicity of Hydrochlorothiazide.

Hydrochlorothiazide (HCTZ) belongs to the thiazide diuretics family that is used for the treatment of hypertension. Enalapril is another drug that is used for the treatment of hypertension. Recently, both drugs were combined in a single medication called vaseretic that showed a strong synergistic effect against hypertension.

Age- and gender-independent association of glutathione S-transferase null polymorphisms with chronic myeloid leukemia.

The glutathione S-transferase (GST) genes encode enzymes that mediate the detoxification of xenobiotics by catalyzing the conjugation of glutathione (GSH) to xenobiotic substrates. The aim of the current study is to investigate the association between GSTT1 and GSTM1 polymorphisms and chronic myeloid leukemia (CML) among Sudanese patients. Patients with CML (n = 115) were recruited to the study from the Radiation and Isotope Centre Khartoum (RICK)-Sudan.

Assessment of biosafety measures in clinical laboratories of Al-Madinah city, Saudi Arabia.

Introduction: Workers in clinical laboratories are exposed to occupational hazards on a daily basis and their health and safety may be threatened if appropriate protective standards are not implemented. The aim of this study was to assess the knowledge and practices of clinical laboratory workers towards biosafety measures, in Al-Madinah city, Saudi Arabia.

Methodology: Clinical laboratory staff was recruited from both the public and private sectors.

Lead exposure among five distinct occupational groups: a comparative study.

This study was conducted to evaluate blood lead concentration among five selected occupational groups. The five groups were: hospital health workers, shop workers, taxi drivers, automobiles mechanics, and wood workers. The groups did not significantly differ among each other in the average of age and work years.