Validity, reliability and accuracy of inertial measurement units (IMUs) to measure angles: application in swimming.

The first objective was to test the validity, reliability and accuracy of paired inertial measurement units (IMUs) to assess absolute angles relative to Vicon and OptiTrack systems. The potential impacts of slow . rapid and intermittent .

Lessons Learned in a Physician Referral to Pediatric Telemental Health Services Program.

Background: This study explores the physician referral and engagement process of a pediatric telemental health program based in a large urban teaching children's hospital, and identifies the processes, strengths and challenges from the perspectives of Primary Care Physicians (PCPs) and telepsychiatrist consultants.

Methods: A mixed methods approach was used. This included an online survey completed by 43 PCPs in Ontario rural communities who had referred patients to the telemental health program.

Perception and action in swimming: Effects of aquatic environment on upper limb inter-segmental coordination.

This study assessed perception-action coupling in expert swimmers by focusing on their upper limb inter-segmental coordination in front crawl. To characterize this coupling, we manipulated the fluid flow and compared trials performed in a swimming pool and a swimming flume, both at a speed of 1.35ms.

Negative childhood experiences alter a prefrontal-insular-motor cortical network in healthy adults: A preliminary multimodal rsfMRI-fMRI-MRS-dMRI study.

Research in humans and animals has shown that negative childhood experiences (NCE) can have long-term effects on the structure and function of the brain. Alterations have been noted in grey and white matter, in the brain's resting state, on the glutamatergic system, and on neural and behavioural responses to aversive stimuli. These effects can be linked to psychiatric disorder such as depression and anxiety disorders that are influenced by excessive exposure to early life stressors.

Access to pyridyl-substituted 1,3,5-triazines from 4H-pyrido[1,3]oxazin-4-ones via a cyclocondensation process.

Pyridyl-substituted 1,3,5-triazines were synthesized in good to excellent yields via an unprecedented one-step cyclocondensation of 4H-pyrido[1,3]oxazin-4-ones with amidines at room temperature or under microwave irradiations. The broad applicability was demonstrated by 33 examples with a variety of amidines and three different 4H-pyrido[1,3]oxazin-4-one chemical series. In addition, a one-pot process from 4H-pyrido[1,3]oxazin-4-one precursors (imide sodium salts) was developed and led to the desired triazines compounds, thus allowing a one-step economy in their global synthetic preparation.

Expeditive access to 2-substituted 4H-pyrido[1,3]oxazin-4-ones via an intramolecular O-arylation.

Unreported 2-substituted 4H-pyrido[e][1,3]oxazin-4-ones are synthesized via an unprecedented intramolecular O-arylation of N-aroyl- and N-heteroaroyl-(iso)nicotinamides under microwave irradiations, in good to excellent yields. The broad applicability was demonstrated by 24 examples with a variety of substituents at the 2-position of the final compounds and 3 possible positions for the nitrogen atom of the pyridine ring. In addition, transformation of one of these compounds into 2-hydroxypyridyl-substituted 1,2,4-triazole and 1,2,4-oxazinone was realized.

Synthesis of bridgehead-substituted azabicyclo[2.2.1]heptane and -[3.3.1]nonane derivatives for the elaboration of α7 nicotinic ligands.

Azabicyclo[2.2.1]heptane and -[3.

Effects of posture and ergometer-specific exercise modality on plasma viscosity and plasma fibrinogen: the role of plasma volume changes.

The aim of the present study was ascertain the effects posture and exercise modality on the main determinants of blood rheology. Thirteen subjects performed two exercise trials, in random order, at approximately 70% VO(2) max for 45-min. One trial was performed on a motorized treadmill at an intensity corresponding to 70% VO(2) max, while the other was performed on a stationary pike at an intensity corresponding to 70% VO(2) max.

Synthesis of new bridgehead substituted azabicyclo-[2.2.1]heptane and -[3.3.1]nonane derivatives as potent and selective α7 nicotinic ligands.

New azabicyclo[2.2.1]heptane and -[3.

Does ambient temperature affect exercise-induced changes in the main determinants of blood rheology?

To ascertain the effects of environmental temperature on blood rheology, ten subjects performed two exercise trials, in random order, at approximately 60% VO(2) max for 45-min. One trial was conducted in thermoneutral environment (20 ± 1°C), while the other was performed in hot dry condition (36 ± 1°C). Venous blood was removed at rest; following exercise and recovery.