Publications by authors named "Oluwatosin Olasheu Omoola"
Thymoquinone ameliorate oxidative stress, GABAergic neuronal depletion and memory impairment through Nrf2/ARE signaling pathway in the dentate gyrus following cypermethrin administration.
Abubakar Lekan Imam Akeem Ayodeji Okesina Fatimo Ajoke Sulaimon Aminu Imam Ruqayyah Yetunde Ibiyeye Oluwatosin Olasheu Omoola
BMC Neurosci
September 2024
Article Synopsis
- - The study investigates how thymoquinone can protect the brain from damage caused by the insecticide cypermethrin, focusing on its effects within the dentate gyrus region responsible for memory and motor functions.
- - Forty adult male rats were divided into five groups, receiving various treatments over 14 days, including combinations of cypermethrin and thymoquinone, followed by tests to assess memory and brain health.
- - Results indicate that thymoquinone improves memory performance and supports brain cell integrity while reducing neurotoxic effects of cypermethrin, suggesting its potential as a treatment for pesticide-related neurotoxicity.